Duggan Lisa, Hood Claire, Warren-Forward Helen, Haque Mamoon, Kron Tomas
Newcastle Mater Misericordiae Hospital, Waratah, NSW 2298, Australia.
Phys Med Biol. 2004 Sep 7;49(17):3831-45. doi: 10.1088/0031-9155/49/17/001.
In many medical procedures where accurate radiation dose measurements are needed, the variation of detector response with x-ray energy is of concern. The response of LiF:Mg,Cu,P TLDs to a range of x-ray energies was analysed in monoenergetic (synchrotron), diagnostic and therapy radiation beams with the aim of implementing this dosimeter into clinical practice where existing dosimetry techniques are limited due to lack of sensitivity or tissue equivalence (e.g. neonatal radiography, mammography and brachytherapy). LiF:Mg,Cu,P TLDs in different forms from two manufacturers (MCP-N: TLD Poland, GR200: SDDML China) were irradiated using x-ray beams covering 10 keV to 18 MVp. Dose readings were compared with an ionization chamber. The effect of different TLD types and annealing cycles on clinical utility was investigated. The measured energy response of LiF:Mg,Cu,P TLDs was fit to a simple model devised by Kron et al (1998 Phys. Med. Biol. 43 3235-59) to describe the variation of TLD response with x-ray energy. If TLDs are handled as recommended in the present paper, the energy response of LiF:Mg,Cu,P deviates by a maximum of 15% from unity and agrees with the model to within 5% or experimental uncertainty between 15 keV and 10 MeV. LiF:Mg,Cu,P TLDs of all forms have consistent and superior energy response compared to the standard material LiF:Mg,Ti and are therefore suitable for a wide range of applications in diagnostic radiology and radiotherapy.
在许多需要精确测量辐射剂量的医疗程序中,探测器响应随X射线能量的变化备受关注。分析了LiF:Mg,Cu,P热释光剂量计(TLD)在单能(同步加速器)、诊断和治疗辐射束中对一系列X射线能量的响应,目的是将这种剂量计应用于临床实践,因为现有的剂量测定技术由于缺乏灵敏度或组织等效性而受到限制(例如新生儿放射摄影、乳腺摄影和近距离放射治疗)。使用覆盖10keV至18MVp的X射线束对来自两家制造商的不同形式的LiF:Mg,Cu,P TLD(MCP-N:波兰TLD公司,GR200:中国SDDML公司)进行照射。将剂量读数与电离室进行比较。研究了不同TLD类型和退火周期对临床应用的影响。将测量的LiF:Mg,Cu,P TLD的能量响应拟合到Kron等人(1998年,《物理医学与生物学》43卷,3235 - 3259页)设计的一个简单模型中,以描述TLD响应随X射线能量的变化。如果按照本文推荐的方法处理TLD,LiF:Mg,Cu,P的能量响应与统一值的最大偏差为15%,并且在15keV至10MeV范围内与模型的偏差在5%以内或实验不确定度范围内。与标准材料LiF:Mg,Ti相比,所有形式的LiF:Mg,Cu,P TLD都具有一致且优异的能量响应,因此适用于诊断放射学和放射治疗中的广泛应用。