Orenstein David M, Hovell Melbourne F, Mulvihill Mary, Keating Kristen K, Hofstetter C Richard, Kelsey Sheryl, Morris Kimberly, Nixon Patricia A
Center for Behavioral Epidemiology and Community Health, 9245 Sky Park Court, Suite 230, San Diego, CA 92123, USA.
Chest. 2004 Oct;126(4):1204-14. doi: 10.1378/chest.126.4.1204.
Exercise has the potential to improve the ability of a patient with cystic fibrosis (CF) to cope with the physical demands of everyday life, and may improve prognosis. The purpose of this study was to compare the effects of a home-based, semi-supervised, upper-body strength-training regimen with a similarly structured aerobic training regimen.
Data were collected during a 1-year randomized clinical trial.
Counselors conducted in-home visits with the participants once per week for the first 8 weeks followed by monthly visits for the remainder of the study.
Sixty-seven patients with CF, aged 8 to 18 years, participated in the trial.
Participants in both exercise conditions were encouraged to exercise at least three times per week for 1 year. Each child in the aerobic group was given a stair-stepping machine, and each child in the upper-body strength training group was given an upper-body-only weight-resistance machine.
Aerobic fitness, pulmonary function, quality of life, and strength were measured at baseline, at 6 months, and at 12 months. Strength training increased the maximum weight lifted for biceps curls significantly more than aerobic training (p < 0.02). However, this differential did not remain significant after control for increase in height. Both training procedures were associated with increased strength (p < 0.002) and physical work capacity (PWC) [p < 0.033].
We concluded that strength and aerobic training may increase upper-body strength, and that both types of training may increase PWC for children with CF. Future trials should be conducted with no-training control subjects and larger samples to increase statistical power.
运动有可能提高囊性纤维化（CF）患者应对日常生活体力需求的能力，并可能改善预后。本研究的目的是比较家庭式、半监督的上肢力量训练方案与结构类似的有氧训练方案的效果。
在一项为期1年的随机临床试验中收集数据。
在研究的前8周，咨询师每周对参与者进行一次家访，之后在研究剩余时间每月进行一次家访。
67名8至18岁的CF患者参与了试验。
两种运动条件下的参与者都被鼓励每周至少锻炼3次，持续1年。有氧训练组的每个孩子都得到一台楼梯踏步机，上肢力量训练组的每个孩子都得到一台仅锻炼上肢的抗阻器械。
在基线、6个月和12个月时测量有氧适能、肺功能、生活质量和力量。力量训练使二头肌弯举的最大举重量增加，显著多于有氧训练（p < 0.02）。然而，在控制身高增加后，这种差异不再显著。两种训练方法都与力量增加（p < 0.002）和体力工作能力（PWC）增加（p < 0.033）相关。
我们得出结论，力量训练和有氧训练可能会增加CF儿童的上肢力量，且两种训练都可能增加其PWC。未来的试验应以无训练对照组和更大样本进行，以提高统计效力。
