Mizuta K, Hashimoto T, Otaka E
Department of Biochemistry and Biophysics, Hiroshima University, Japan.
Nucleic Acids Res. 1992 Mar 11;20(5):1011-6. doi: 10.1093/nar/20.5.1011.
We isolated and sequenced a gene, YL8A, encoding ribosomal protein YL8 of Saccharomyces cerevisiae. It is one of the two duplicated genes encoding YL8 and is located on chromosome VII while the other is on chromosome XVI. The haploid strains carrying disrupted YL8A grew more slowly than the parent strain. The open reading frame is interrupted with two introns. The predicted amino acid sequence reveals that yeast YL8 is a homolog of mammalian ribosomal protein L7, E.coli L30 and others.
我们分离并测序了一个基因YL8A，它编码酿酒酵母的核糖体蛋白YL8。它是编码YL8的两个重复基因之一，位于第七条染色体上，而另一个位于第十六条染色体上。携带被破坏的YL8A的单倍体菌株比亲本菌株生长得更慢。开放阅读框被两个内含子打断。预测的氨基酸序列表明，酵母YL8是哺乳动物核糖体蛋白L7、大肠杆菌L30等的同源物。
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