Schwan T G, Schrumpf M E, Gage K L, Gilmore R D
Arthropod-Borne Diseases Section, Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana 59840.
J Clin Microbiol. 1992 Mar;30(3):735-8. doi: 10.1128/jcm.30.3.735-738.1992.
Five serovars of Leptospira interrogans, Leptospira biflexa, Leptonema illini, and Rickettsia rickettsii were examined and found not to contain the 39-kDa antigen (P39) of Borrelia burgdorferi, the Lyme disease spirochete. The specificity of this antigen and its reactivity with human Lyme disease sera should exclude the possibility of false-positive serum samples from patients having had either leptospirosis or Rocky Mountain spotted fever, as well as tick-borne relapsing fever and syphilis, as reported previously (W.J. Simpson, M. E. Schrumpf, and T. G. Schwan, J. Clin. Microbiol. 28:1329-1337, 1990).
对问号钩端螺旋体的五个血清型、双曲钩端螺旋体、伊利诺伊细螺旋体和立氏立克次体进行了检测，发现它们均不含有莱姆病螺旋体——伯氏疏螺旋体的39-kDa抗原（P39）。如先前报道（W.J. 辛普森、M.E. 施伦普夫和T.G. 施万，《临床微生物学杂志》28:1329 - 1337, 1990），该抗原的特异性及其与人莱姆病血清的反应性应排除曾患钩端螺旋体病或落基山斑疹热患者血清样本出现假阳性的可能性，以及蜱传回归热和梅毒患者血清样本出现假阳性的可能性。
