产IMP-1型铜绿假单胞菌在新加坡两家医院的克隆传播。

Clonal spread of IMP-1-producing Pseudomonas aeruginosa in two hospitals in Singapore.

作者信息

Koh Tse Hsien, Wang Grace Chee Yeng, Sng Li-Hwei

机构信息

Department of Pathology, Singapore General Hospital, 1 Hospital Dr., 169608 Singapore, Singapore.

出版信息

J Clin Microbiol. 2004 Nov;42(11):5378-80. doi: 10.1128/JCM.42.11.5378-5380.2004.

DOI:10.1128/JCM.42.11.5378-5380.2004

PMID:15528748

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC525177/

Abstract

Thirty-six isolates of carbapenem-resistant Pseudomonas aeruginosa were studied. Pulsed-field gel electrophoresis revealed the presence of two clones. One clone carried a bla(IMP-1) gene identical to that first described in Japan. The other clone carried a bla(IMP-1) variant containing four silent mutations. One isolate with a unique pulsed-field gel electrophoresis pattern contained bla(IMP-7).

摘要

对36株耐碳青霉烯类铜绿假单胞菌分离株进行了研究。脉冲场凝胶电泳显示存在两个克隆。一个克隆携带与日本首次描述的bla(IMP-1)基因相同的基因。另一个克隆携带一个包含四个沉默突变的bla(IMP-1)变体。一株具有独特脉冲场凝胶电泳图谱的分离株含有bla(IMP-7)。