在新加坡分离出的荧光假单胞菌中发现的IMP-1和一种新型金属β-内酰胺酶VIM-6 。
IMP-1 and a novel metallo-beta-lactamase, VIM-6, in fluorescent pseudomonads isolated in Singapore.
作者信息
Koh Tse Hsien, Wang Grace Chee Yeng, Sng Li-Hwei
机构信息
Department of Pathology, Singapore General Hospital, 1 Hospital Dr., 168608 Singapore, Singapore.
出版信息
Antimicrob Agents Chemother. 2004 Jun;48(6):2334-6. doi: 10.1128/AAC.48.6.2334-2336.2004.
Abstract
Four carbapenem-resistant Pseudomonas spp. were isolated from patients in Singapore. One Pseudomonas putida isolate contained a bla(IMP-1) identical to that first described in Japan. The sequence of a variant bla(IMP-1) in Pseudomonas fluorescens contained four silent mutations compared with the original sequence. The remaining P. putida isolates contained bla(VIM-6), a novel VIM gene variant.
摘要
从新加坡的患者中分离出了4株耐碳青霉烯类假单胞菌属细菌。一株恶臭假单胞菌分离株携带的bla(IMP-1)与在日本首次描述的相同。荧光假单胞菌中一种变异的bla(IMP-1)序列与原始序列相比有4个沉默突变。其余的恶臭假单胞菌分离株携带bla(VIM-6)，这是一种新型的VIM基因变体。
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