Hajri Selma, Blum Jennifer, Gueddana Nabiha, Saadi Habib, Maazoun Leila, Chélli Hela, Dabash Rasha, Winikoff Beverly
Private Provider, Tunis, Tunisia.
Contraception. 2004 Dec;70(6):487-91. doi: 10.1016/j.contraception.2004.06.012.
From November 2000 to July 2001, 321 consenting women were enrolled at four sites across the country in an effort to demonstrate that mifepristone medical abortion could safely be used by providers throughout Tunisia. Women who met the study's inclusion criteria were given 200 mg oral mifepristone and offered the choice of taking 400 microg oral misoprostol 2 days later either at home or at the clinic. At follow-up, women were examined to determine completed abortion status and surveyed to gauge their satisfaction with the method. Ninety-six percent of women had a successful abortion using this method. Women expressed a strong preference for home use of misoprostol, indicating that it is more confidential (34%), easier (28%) and requires fewer clinic visits (28%). The high rate of success, demonstrated safety and acceptability of the method in new facilities and with new providers suggests that medical abortion can be safely expanded to new settings with reasonable levels of training and supervision.
2000年11月至2001年7月,全国四个地点招募了321名同意参与的女性,目的是证明米非司酮药物流产在突尼斯各地的医疗服务提供者中可以安全使用。符合研究纳入标准的女性服用了200毫克口服米非司酮,并可选择在两天后在家中或诊所服用400微克口服米索前列醇。随访时,对女性进行检查以确定流产是否完成,并进行调查以评估她们对该方法的满意度。96%的女性使用该方法成功流产。女性强烈倾向于在家中使用米索前列醇,表明这样更私密(34%)、更方便(28%)且需要就诊的次数更少(28%)。该方法在新机构和新医疗服务提供者中的高成功率、已证实的安全性和可接受性表明,在进行合理程度的培训和监督的情况下,药物流产可以安全地扩展到新的环境中。