Kokol R, Berger C, Haas J, Kopera D
Klinik für Dermatologie und Venerologie, Universität, Graz, Osterreich.
Hautarzt. 2005 Jun;56(6):570-5. doi: 10.1007/s00105-004-0864-7.
Venous leg ulcers (ulcera crurum venosa) are frequently seen in elderly patients. It has been suggested that low level laser irradiation has a biostimulative and wound healing effect; however, this has not yet been clinically verified by controlled studies.
The difference in size reduction of leg ulcers with and without low level laser or placebo laser treatment was measured in 44 patients randomised into two treatment groups (685-nm low level laser and placebo laser) or a control group which served to quantify the effect of laser application. All patients received standardized wound care.
The aim of the study was to compare the effectiveness of low level laser irradiation with that of a placebo "light source". The size of the ulcers was planimetrically measured at baseline (day 1), at the end of therapy (day 28) and 2 months later (day 90). The difference in wound size was evaluated.
There were no statistically significant differences in reduction of wound size between the three groups, thus suggesting that low level laser light does not have any stimulatory effect on wound healing in ulcera crurum venosa.
腿部静脉溃疡在老年患者中很常见。有人提出低强度激光照射具有生物刺激和促进伤口愈合的作用；然而，这尚未通过对照研究得到临床验证。
将44例患者随机分为两个治疗组（685纳米低强度激光组和安慰剂激光组）或一个对照组，测量接受和未接受低强度激光或安慰剂激光治疗的腿部溃疡面积缩小的差异，对照组用于量化激光照射的效果。所有患者均接受标准化伤口护理。
本研究的目的是比较低强度激光照射与安慰剂“光源”的有效性。在基线（第1天）、治疗结束时（第28天）和2个月后（第90天）用平面测量法测量溃疡大小。评估伤口大小的差异。
三组之间伤口大小缩小没有统计学上的显著差异，因此表明低强度激光对腿部静脉溃疡的伤口愈合没有任何刺激作用。
