Kohn Robert, Saxena Shekhar, Levav Itzhak, Saraceno Benedetto
Department of Psychiatry and Human Behavior, Brown University, Providence, RI, USA.
Bull World Health Organ. 2004 Nov;82(11):858-66. Epub 2004 Dec 14.
Mental disorders are highly prevalent and cause considerable suffering and disease burden. To compound this public health problem, many individuals with psychiatric disorders remain untreated although effective treatments exist. We examine the extent of this treatment gap. We reviewed community-based psychiatric epidemiology studies that used standardized diagnostic instruments and included data on the percentage of individuals receiving care for schizophrenia and other non-affective psychotic disorders, major depression, dysthymia, bipolar disorder, generalized anxiety disorder (GAD), panic disorder, obsessive-compulsive disorder (OCD), and alcohol abuse or dependence. The median rates of untreated cases of these disorders were calculated across the studies. Examples of the estimation of the treatment gap for WHO regions are also presented. Thirty-seven studies had information on service utilization. The median treatment gap for schizophrenia, including other non-affective psychosis, was 32.2%. For other disorders the gap was: depression, 56.3%; dysthymia, 56.0%; bipolar disorder, 50.2%; panic disorder, 55.9%; GAD, 57.5%; and OCD, 57.3%. Alcohol abuse and dependence had the widest treatment gap at 78.1%. The treatment gap for mental disorders is universally large, though it varies across regions. It is likely that the gap reported here is an underestimate due to the unavailability of community-based data from developing countries where services are scarcer. To address this major public health challenge, WHO has adopted in 2002 a global action programme that has been endorsed by the Member States.
精神障碍极为普遍,会造成巨大痛苦和疾病负担。更为复杂的是,尽管存在有效的治疗方法,但许多患有精神疾病的人仍未得到治疗。我们研究了这一治疗缺口的程度。我们回顾了基于社区的精神疾病流行病学研究,这些研究使用了标准化诊断工具,并纳入了有关精神分裂症及其他非情感性精神病性障碍、重度抑郁症、心境恶劣障碍、双相情感障碍、广泛性焦虑障碍(GAD)、惊恐障碍、强迫症(OCD)以及酒精滥用或依赖患者接受治疗比例的数据。在各项研究中计算了这些疾病未治疗病例的中位数比例。还给出了世卫组织各区域治疗缺口估计值的示例。37项研究提供了服务利用情况的信息。精神分裂症(包括其他非情感性精神病)的中位数治疗缺口为32.2%。其他疾病的缺口为:抑郁症,56.3%;心境恶劣障碍,56.0%;双相情感障碍,50.2%;惊恐障碍,55.9%;广泛性焦虑障碍,57.5%;强迫症,57.3%。酒精滥用和依赖的治疗缺口最大,为78.1%。精神障碍的治疗缺口普遍很大,尽管各区域有所不同。由于难以获取服务更为匮乏的发展中国家基于社区的数据,这里报告的缺口很可能被低估了。为应对这一重大公共卫生挑战,世卫组织于2002年通过了一项得到会员国认可的全球行动计划。