Korotkova Natalia, Lidstrom Mary E, Chistoserdova Ludmila
Department of Chemical Engineering, University of Washington, Seattle, WA 98195, USA.
J Bacteriol. 2005 Feb;187(4):1523-6. doi: 10.1128/JB.187.4.1523-1526.2005.
The glyoxylate regeneration cycle (GRC) operates in serine cycle methylotrophs to effect the net conversion of acetyl coenzyme A to glyoxylate. Mutants have been generated in several genes involved in the GRC, and phenotypic analysis has been carried out to clarify their role in this cycle.
乙醛酸再生循环(GRC)在丝氨酸循环甲基营养菌中发挥作用,实现乙酰辅酶A到乙醛酸的净转化。已在参与GRC的多个基因中产生了突变体,并进行了表型分析以阐明它们在该循环中的作用。