Thomas B J
University of California, Los Angeles School of Medicine.
Orthop Clin North Am. 1992 Apr;23(2):347-58.
Formation of heterotopic bone can cause pain and limit motion, thus ruin what would otherwise have been an excellent result after total hip arthroplasty. The cause of bone formation remains controversial, and diphosphonates have been ineffective in its prevention. Radiotherapy and nonsteroidal anti-inflammatory drugs, however, are effective preventative agents. Once the bone is formed, however, surgical excision is the only effective treatment.
异位骨的形成会导致疼痛并限制活动，从而破坏全髋关节置换术后原本可能非常好的效果。骨形成的原因仍存在争议，双膦酸盐在预防方面一直无效。然而，放疗和非甾体抗炎药是有效的预防药物。然而，一旦骨形成，手术切除是唯一有效的治疗方法。
