Department of Agricultural Biotechnology, Seoul National University, Seoul 151-921, Republic of Korea.
J Med Entomol. 2009 Nov;46(6):1420-3. doi: 10.1603/033.046.0624.
The toxicity of several compounds isolated from Asarum heterotropoides root steam distillate to third-instar larvae of Culex pipiens pallens Coquillett, Aedes aegypti (L.), and Ochlerotatus togoi Theobald was examined using a direct contact mortality bioassay. Safrole was the most toxic constituent to Cx. p. pallens and Ae. aegypti larvae, whereas terpinolene was most toxic to Oc. togoi. However, LC50 values of these three mosquito larvae to both essential oils as well as the remainder of the 26 compounds identified in A. heterotropoides were considerably greater than for fenthion or temephos. However, we suggest that constituents of A. heterotropoides root steam distillate merit further study as potential mosquito larvicides due to global efforts to reduce the level of highly toxic synthetic pesticides in the aquatic environment.
采用直接接触致死生物测定法，检测了从细辛根汽蒸馏中分离得到的几种化合物对三龄淡色库蚊幼虫、埃及伊蚊和白纹伊蚊的毒性。黄樟素是对淡色库蚊和埃及伊蚊幼虫毒性最强的成分，而萜品烯对三带喙库蚊毒性最强。然而，这三种蚊虫幼虫对两种精油以及在细辛中鉴定出的 26 种化合物的其余成分的 LC50 值均明显大于倍硫磷或敌百虫。然而，我们认为细辛根汽蒸馏的成分值得进一步研究，因为全球都在努力降低水生环境中高度有毒的合成农药的水平，它们可能具有作为潜在的蚊虫杀虫剂的潜力。
