Jambazian Pera R, Haddad Ella, Rajaram Sujatha, Tanzman Jay, Sabaté Joan
School of Kinesiology and Nutritional Science, California State University, Los Angeles, CA, USA.
J Am Diet Assoc. 2005 Mar;105(3):449-54. doi: 10.1016/j.jada.2004.12.002.
The objective of this study was to assess the dose-response effect of almond intake on plasma and red blood cell tocopherol concentrations in healthy adults enrolled in a randomized, crossover feeding trial. Participants were 16 healthy men and women, aged 41+/-13 years. After a 2-week run-in period, participants were fed three diets for 4 weeks each: a control diet, a low-almond diet, and a high-almond diet, in which almonds contributed 0%, 10%, and 20% of total energy, respectively. Changes in blood tocopherol levels were assayed by high pressure liquid chromatography. Incorporating almonds into the diet helped meet the revised Recommended Dietary Allowance of 15 mg/day alpha-tocopherol and increased lipid-adjusted plasma and red blood cell alpha-tocopherol concentrations. A significant dose-response effect was observed between percent energy in the diet from almonds and plasma ratio of alpha-tocopherol to total cholesterol.
本研究的目的是在一项随机交叉喂养试验的健康成年人中，评估杏仁摄入量对血浆和红细胞生育酚浓度的剂量反应效应。参与者为16名健康男性和女性，年龄41±13岁。经过2周的适应期后，参与者分别接受三种饮食，每种饮食持续4周：对照饮食、低杏仁饮食和高杏仁饮食，其中杏仁分别占总能量的0%、10%和20%。通过高压液相色谱法测定血液生育酚水平的变化。将杏仁纳入饮食有助于达到修订后的每日膳食推荐摄入量15毫克α-生育酚，并提高了脂质调整后的血浆和红细胞α-生育酚浓度。在饮食中杏仁所占能量百分比与α-生育酚与总胆固醇的血浆比率之间观察到显著的剂量反应效应。
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