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在中国老年人群中使用非接触眼压计测量眼压:石牌眼研究

Intraocular pressure measured with a noncontact tonometer in an elderly Chinese population: the Shihpai Eye Study.

作者信息

Lin Hsin-Yi, Hsu Wen-Ming, Chou Pesus, Liu Catherine J, Chou Joe C, Tsai Su-Ying, Cheng Ching-Yu

机构信息

Department of Ophthalmology, Taipei Veterans General Hospital, Taipei, Taiwan.

出版信息

Arch Ophthalmol. 2005 Mar;123(3):381-6. doi: 10.1001/archopht.123.3.381.

Abstract

OBJECTIVE

To determine the distribution of intraocular pressure (IOP) as measured by a noncontact tonometer (NCT) and risk factors responsible for ocular hypertension in elderly Chinese people.

DESIGN

Population-based study of randomly sampled Chinese people 65 years and older in Shihpai, Taipei, Taiwan.

MAIN OUTCOME MEASURES

Participants completed an interview and underwent a physical examination and a standardized ophthalmic examination, including IOP measurement with the NCT. People with a history of glaucoma were excluded. Risk factors were assessed using multivariate regression analysis.

RESULTS

Of 1361 study participants examined, 1292 (95.4%) had no history of glaucoma and were therefore included in the study. Their mean +/- SD IOP was 12.9 +/- 3.1 mm Hg. The IOP decreased significantly (P<.001) with age, changing from 13.3 +/- 3.0 mm Hg in participants aged 65 to 69 years to 11.6 +/- 2.8 mm Hg in those 80 years and older. Women had significantly higher IOP than men (P<.001). In the multivariate regression analysis, decreasing age, female sex, increasing systolic blood pressure, a history of diabetes, and alcohol drinking were significantly associated with increasing IOP.

CONCLUSIONS

The distribution of IOP in elderly Chinese people is similar to that found in other East Asian people, with a negative age-IOP relationship. The mean IOP values in this elderly Chinese population were lower than in white people but higher than in Japanese people in similarly aged groups. Establishing the epidemiologic characteristics of IOP with the NCT is important for the mass screening of ocular hypertension.

摘要

目的

确定通过非接触眼压计(NCT)测量的眼压(IOP)分布情况以及中国老年人高眼压的危险因素。

设计

对台湾台北市石牌65岁及以上的中国人进行基于人群的随机抽样研究。

主要观察指标

参与者完成访谈并接受体格检查和标准化眼科检查,包括使用NCT测量眼压。排除有青光眼病史的人。使用多变量回归分析评估危险因素。

结果

在1361名接受检查的研究参与者中,1292人(95.4%)无青光眼病史,因此被纳入研究。他们的平均眼压±标准差为12.9±3.1 mmHg。眼压随年龄显著降低(P<0.001),从65至69岁参与者的13.3±3.0 mmHg降至80岁及以上参与者的11.6±2.8 mmHg。女性眼压显著高于男性(P<0.001)。在多变量回归分析中,年龄降低、女性、收缩压升高、糖尿病史和饮酒与眼压升高显著相关。

结论

中国老年人的眼压分布与其他东亚人群相似,眼压与年龄呈负相关。该中国老年人群的平均眼压值低于白人,但高于同龄组的日本人。通过NCT确定眼压的流行病学特征对于高眼压的大规模筛查很重要。

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