Schwandt Leonora Q, van Weissenbruch Ranny, van der Mei Henny C, Busscher Henk J, Albers Frans W J
Department of Otorhinolaryngology, University Medical Centre Groningen, P. O. Box 30.001, 9700 RB Groningen, The Netherlands.
Head Neck. 2005 Jun;27(6):471-7. doi: 10.1002/hed.20180.
Reduction of biofilm formation on tracheoesophageal voice prostheses by certain dairy products might extend their clinical lifetime. The purpose of this study was to determine the influence of certain dairy products on voice prosthetic biofilms and lifetimes in vitro and in vivo.
The in vitro results were accomplished using an artificial throat. The lifetimes of Provox2 prostheses were evaluated in a patient group that daily consumed the evaluated products.
Buttermilk and Yakult Light fermented milk decreased the amount of bacteria on voice prostheses but stimulated yeast prevalence in vitro. Concurrently, lifetimes of voice prostheses in patients consuming buttermilk were not significantly different, whereas patients consuming Yakult Light fermented milk drink had a significantly (p < .01) increased prosthesis lifetime by a factor of 3.76.
Yakult Light fermented milk drink reduced biofilm formation on Provox2 prostheses in vitro and in vivo and significantly increased prosthesis lifetime. In vivo, no significant effects were observed for patients consuming buttermilk.
某些乳制品减少气管食管语音假体上生物膜的形成可能会延长其临床使用寿命。本研究的目的是确定某些乳制品在体外和体内对语音假体生物膜及使用寿命的影响。
体外实验结果通过人工喉获得。在每日食用评估产品的患者组中评估Provox2假体的使用寿命。
酪乳和养乐多低糖发酵乳减少了语音假体上的细菌数量，但在体外刺激了酵母菌的滋生。同时，食用酪乳的患者语音假体的使用寿命无显著差异，而食用养乐多低糖发酵乳饮料的患者假体使用寿命显著（p <.01）延长，延长系数为3.76。
养乐多低糖发酵乳饮料在体外和体内均减少了Provox2假体上生物膜的形成，并显著延长了假体使用寿命。在体内，食用酪乳的患者未观察到显著影响。
