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布氏杆菌溃疡(溃疡分枝杆菌感染):新见解,疾病控制新希望。

Buruli ulcer (M. ulcerans infection): new insights, new hope for disease control.

作者信息

Johnson Paul D R, Stinear Timothy, Small Pamela L C, Pluschke Gerd, Merritt Richard W, Portaels Francoise, Huygen Kris, Hayman John A, Asiedu Kingsley

机构信息

Department of Infectious Diseases, Austin Health, Heidelberg, Australia.

出版信息

PLoS Med. 2005 Apr;2(4):e108. doi: 10.1371/journal.pmed.0020108. Epub 2005 Apr 26.

DOI:10.1371/journal.pmed.0020108
PMID:15839744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1087202/
Abstract

Buruli ulcer is a disease of skin and soft tissue caused by It can leave affected people scarred and disabled. What are the prospects for disease control?

摘要

布鲁里溃疡是一种由[病原体未提及]引起的皮肤和软组织疾病。它会使患者留下疤痕并致残。疾病控制的前景如何?

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2d/1087202/0188a12e2f7e/pmed.0020108.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2d/1087202/60aeaa543856/pmed.0020108.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2d/1087202/2926248aa328/pmed.0020108.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2d/1087202/bd39a179c940/pmed.0020108.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2d/1087202/0188a12e2f7e/pmed.0020108.g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2d/1087202/60aeaa543856/pmed.0020108.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2d/1087202/2926248aa328/pmed.0020108.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2d/1087202/bd39a179c940/pmed.0020108.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3a2d/1087202/0188a12e2f7e/pmed.0020108.g004.jpg

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本文引用的文献

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A new mycobacterial infection in man.人类的一种新的分枝杆菌感染。
J Pathol Bacteriol. 1948 Jan;60(1):93-122.
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Dry-reagent-based PCR as a novel tool for laboratory confirmation of clinically diagnosed Mycobacterium ulcerans-associated disease in areas in the tropics where M. ulcerans is endemic.基于干试剂的聚合酶链反应作为一种新型工具,用于在溃疡分枝杆菌流行的热带地区对临床诊断的溃疡分枝杆菌相关疾病进行实验室确诊。
探索分枝杆菌内酯——布鲁里溃疡的独特致病毒素:生物合成、合成途径、诊断生物标志物及治疗潜力
Toxins (Basel). 2024 Dec 6;16(12):528. doi: 10.3390/toxins16120528.
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Determinants of CRISPR Cas12a nuclease activation by DNA and RNA targets.CRISPR Cas12a 核酸酶对 DNA 和 RNA 靶标的激活决定因素。
Nucleic Acids Res. 2024 May 8;52(8):4502-4522. doi: 10.1093/nar/gkae152.
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Emergence and spread of at different geographic scales.在不同地理尺度上的出现和传播。
Microbiol Spectr. 2024 Apr 2;12(4):e0382723. doi: 10.1128/spectrum.03827-23. Epub 2024 Mar 5.
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Mycobacterium ulcerans not detected by PCR on human skin in Buruli ulcer endemic areas of south eastern Australia.在澳大利亚东南部的布鲁里溃疡流行地区,PCR 未能在人类皮肤上检测到溃疡分枝杆菌。
PLoS Negl Trop Dis. 2023 Oct 12;17(10):e0011272. doi: 10.1371/journal.pntd.0011272. eCollection 2023 Oct.
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Type-I interferons promote innate immune tolerance in macrophages exposed to Mycobacterium ulcerans vesicles.I 型干扰素促进分枝杆菌囊泡暴露的巨噬细胞固有免疫耐受。
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Int J Mol Sci. 2023 Apr 12;24(8):7151. doi: 10.3390/ijms24087151.
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Assessing water-related risk factors for Buruli ulcer: a case-control study in Ghana.评估布鲁里溃疡与水相关的风险因素:加纳的一项病例对照研究。
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