Thomson B M, Grounds P R
Food Addit Contam. 2005 Jan;22(1):65-72. doi: 10.1080/02652030400027920.
Exposure to bisphenol A (BPA) from the consumption of canned and bottled food has been determined for New Zealand adults. Eighty different canned foods purchased from retail outlets in Christchurch, New Zealand, between November 2003 and February 2004 were analysed for BPA concentration by gas chromatography/mass spectrometry. BPA was detected in all foods analysed except for soft drinks. Concentrations ranged from < 10 to 29 microg kg(-1), except for individual samples of tuna, corned beef and coconut cream, which were 109, 98 and 191 microg kg(-1) , respectively. The limit of quantitation was <10 microg kg(-1) for foods of low fat content (< 1%) and <20 microg kg(-1) for foods containing >1% fat. Mean concentration data were combined with 24-h dietary recall information for 4399 individual consumers. Mean and maximum exposures were 0.008 and 0.29 microg kg(-1) bw day(-1), respectively, well below the temporary tolerable daily intake of 10 microg kg(-1) bw day(-1) given by the European Commission in 2002. The results of the present survey suggest that the levels of BPA identified in canned foods are unlikely to be of concern to adult health, and there is no reason for consumers to change their consumption patterns as a result of these findings. When the concentration data found in the current survey are applied to an oestrogenicity model for an adult male, the contribution of BPA to the total oestrogenicity from 16 food components is 7%. The impact of this level of oestrogenicity remains unclear.
已对新西兰成年人因食用罐装和瓶装食品而接触双酚A(BPA)的情况进行了测定。2003年11月至2004年2月期间,从新西兰克赖斯特彻奇的零售店购买了80种不同的罐装食品,采用气相色谱/质谱法分析其双酚A浓度。除软饮料外,在所有分析的食品中均检测到双酚A。浓度范围为<10至29微克/千克,金枪鱼、咸牛肉和椰奶的个别样本除外,其浓度分别为109、98和191微克/千克。低脂含量(<1%)食品的定量限为<10微克/千克,脂肪含量>1%食品的定量限为<20微克/千克。将平均浓度数据与4399名个体消费者的24小时饮食回忆信息相结合。平均暴露量和最大暴露量分别为0.008和0.29微克/千克体重/天,远低于欧盟委员会2002年规定的10微克/千克体重/天的临时每日耐受摄入量。本次调查结果表明,罐装食品中确定的双酚A水平不太可能对成年人健康构成担忧,消费者没有理由因这些发现而改变其消费模式。当将本次调查中发现的浓度数据应用于成年男性的雌激素活性模型时,双酚A对16种食物成分总雌激素活性的贡献为7%。这种雌激素活性水平的影响仍不清楚。