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机器人辅助根治性肾切除术的可行性——单机构初步研究结果

Feasibility of robotic radical nephrectomy--initial results of single-institution pilot study.

作者信息

Klingler Douglas W, Hemstreet George P, Balaji K C

机构信息

Division of Urological Surgery, Department of Surgery, University of Nebraska Medical Center, Omaha, Nebraska 68198-2360, USA.

出版信息

Urology. 2005 Jun;65(6):1086-9. doi: 10.1016/j.urology.2004.12.020.

Abstract

OBJECTIVES

To report our initial experience and the utility of the da Vinci surgical robotic system (DSRS) for performing robotic radical nephrectomy (RRN). The DSRS has been increasingly evaluated to determine its feasibility for assisting surgeons in major urologic procedures.

METHODS

The perioperative outcomes of the first five RRNs performed at our institution were analyzed to establish the safety and utility of the DSRS in performing RRN.

RESULTS

Five male patients with a median age of 72 years (range 45 to 78) underwent RRN. The median body mass index, operative time, intraoperative blood loss, postoperative decrease in hemoglobin, postoperative rise in serum creatinine, postoperative morphine use, hospital stay, kidney size, and tumor size was 28 (range 20.9 to 32.9), 321 minutes (range 246 to 437), 150 mL (range 25 to 1500), 1.4 g/dL (range 0.2 to 3.5), 0.6 mg/dL (range 0.5 to 0.7), 28 mg (range 10 to 212), 3 days (range 1 to 5), 430 cm3 (range 158 to 1387), and 66 cm3 (range 29 to 120), respectively. One RRN was converted to hand-assisted laparoscopy because of bleeding from the left renal vein. No perioperative morbidities or mortalities occurred. The final pathologic examination revealed conventional clear cell carcinoma in 4 patients (1 with pT1a, 2 with pT1b, and 1 with T3a) and a benign cyst in 1 patient.

CONCLUSIONS

The results of our study have confirmed that RRN is a feasible and viable alternative for performing radical nephrectomy. A larger randomized study incorporating cost and outcome comparisons with laparoscopic and open radical nephrectomy is needed before wider application of RRN.

摘要

目的

报告我们使用达芬奇手术机器人系统(DSRS)进行机器人根治性肾切除术(RRN)的初步经验及实用性。DSRS已得到越来越多的评估,以确定其在协助外科医生进行主要泌尿外科手术方面的可行性。

方法

分析我院进行的前5例RRN的围手术期结果,以确定DSRS在进行RRN时的安全性和实用性。

结果

5例男性患者接受了RRN,中位年龄为72岁(范围45至78岁)。中位体重指数、手术时间、术中失血、术后血红蛋白下降、术后血清肌酐升高、术后吗啡用量、住院时间、肾脏大小和肿瘤大小分别为28(范围20.9至32.9)、321分钟(范围246至437)、150 mL(范围25至1500)、1.4 g/dL(范围0.2至3.5)、0.6 mg/dL(范围0.5至0.7)、28 mg(范围10至212)、3天(范围1至5)、430 cm³(范围158至1387)和66 cm³(范围29至120)。1例RRN因左肾静脉出血转为手辅助腹腔镜手术。未发生围手术期并发症或死亡。最终病理检查显示4例为传统透明细胞癌(1例为pT1a,2例为pT1b,1例为T3a),1例为良性囊肿。

结论

我们的研究结果证实,RRN是进行根治性肾切除术的一种可行替代方法。在RRN更广泛应用之前,需要进行一项更大规模的随机研究,纳入与腹腔镜和开放根治性肾切除术的成本及结果比较。

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