Nichols Jason J, Ziegler Corrie, Mitchell G Lynn, Nichols Kelly K
Ohio State University, Columbus, 43218, USA.
Invest Ophthalmol Vis Sci. 2005 Jun;46(6):1911-4. doi: 10.1167/iovs.04-1294.
To compare self-reported dry eye disease across contact lens wearers, spectacles wearers, and clinical emmetropes (i.e., those not requiring refractive correction).
The survey included two symptom questions (dryness and light sensitivity) that inquired about frequency and intensity at three times of day (morning, afternoon, and evening) and a self-perception question (i.e., Do you think you have dry eyes?). Dryness and light sensitivity scales were then calculated, summed, and scored, providing a dry eye classification. Logistic regression (binary and multinomial) and analysis of covariance were used to examine the relation between mode of refractive correction and dry eye status, frequency of symptoms, and diurnal change in symptom intensity.
Overall, 893 surveys were completed, and the age-adjusted frequency of dry eye in the sample was 28.7%, with 3.5% of the sample reporting severe symptoms (at least grade 4 of a possible 5 for both symptoms). Contact lens wearers were most likely to report dry eye disease (52.3%), followed by spectacle wearers (23.9%) and clinical emmetropes (7.1%). Adjustment for age and gender showed that contact lens (adjusted odds ratio = 12.37, 95% confidence interval = 7.55-20.26) and spectacle wearers (adjusted odds ratio = 2.06, 95% confidence interval = 1.12-3.80) were more likely than emmetropes to report dry eye problems. After adjustment for age and gender, contact lens wearers were shown to be more likely to experience frequent symptoms and an increase in symptoms throughout the day (F = 51.4, P < 0.0001).
The frequency of self-reported dry eye is high, especially in contact lens wearers.
比较隐形眼镜佩戴者、眼镜佩戴者和临床正视者(即那些不需要屈光矫正的人)自我报告的干眼疾病情况。
该调查包括两个症状问题(干涩和畏光),询问一天中三个时间段(早晨、下午和晚上)的频率和强度,以及一个自我认知问题(即,你认为自己有干眼吗?)。然后计算、汇总并评分干涩和畏光量表,得出干眼分类。采用逻辑回归(二元和多项)及协方差分析来检验屈光矫正方式与干眼状态、症状频率及症状强度的昼夜变化之间的关系。
总体而言,共完成893份调查问卷,样本中经年龄调整后的干眼频率为28.7%,其中3.5%的样本报告有严重症状(两种症状在可能的5级中至少为4级)。隐形眼镜佩戴者最有可能报告患有干眼疾病(52.3%),其次是眼镜佩戴者(23.9%)和临床正视者(7.1%)。对年龄和性别进行调整后显示,隐形眼镜佩戴者(调整后的优势比 = 12.37, 95%置信区间 = 7.55 - 20.26)和眼镜佩戴者(调整后的优势比 = 2.06, 95%置信区间 = 1.12 - 3.80)比正视者更有可能报告干眼问题。在对年龄和性别进行调整后,隐形眼镜佩戴者更有可能出现频繁症状且全天症状加重(F = 51.4, P < 0.0001)。
自我报告的干眼频率很高,尤其是在隐形眼镜佩戴者中。