• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

寄生蠕虫的组织迁移——一种免疫逃避策略?

Tissue migration by parasitic helminths - an immunoevasive strategy?

作者信息

Mulcahy Grace, O'Neill Sandra, Fanning June, McCarthy Elaine, Sekiya Mary

机构信息

Department of Veterinary Microbiology and Parasitology, Faculty of Veterinary Medicine and Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

出版信息

Trends Parasitol. 2005 Jun;21(6):273-7. doi: 10.1016/j.pt.2005.04.003.

DOI:10.1016/j.pt.2005.04.003
PMID:15922248
Abstract

Migration through host tissues has major costs for parasitic helminths in terms of energy expenditure, risks of attrition and the need to adapt to varying physicochemical environments. Nevertheless, such migratory phases seem to confer a specific survival advantage. One reason for this might be the avoidance of specific host immune-defence mechanisms designed to protect against threats at mucosal surfaces.

摘要

对于寄生性蠕虫而言,在宿主体内组织中移行在能量消耗、损耗风险以及适应不同物理化学环境的需求方面代价高昂。然而,这样的移行阶段似乎赋予了特定的生存优势。其原因之一可能是避开了旨在抵御黏膜表面威胁的特定宿主免疫防御机制。

相似文献

1
Tissue migration by parasitic helminths - an immunoevasive strategy?寄生蠕虫的组织迁移——一种免疫逃避策略?
Trends Parasitol. 2005 Jun;21(6):273-7. doi: 10.1016/j.pt.2005.04.003.
2
Immune regulation by helminth parasites: cellular and molecular mechanisms.蠕虫寄生虫的免疫调节:细胞和分子机制
Nat Rev Immunol. 2003 Sep;3(9):733-44. doi: 10.1038/nri1183.
3
Natural helper cells: a new player in the innate immune response against helminth infection.天然辅助细胞:固有免疫反应抵抗寄生虫感染的新角色。
Adv Immunol. 2010;108:21-44. doi: 10.1016/B978-0-12-380995-7.00002-1.
4
[The problem of tissue parasitism].[组织寄生问题]
Parazitologiia. 1982 Jul-Aug;16(4):265-73.
5
Granulocytes: effector cells or immunomodulators in the immune response to helminth infection?粒细胞:寄生虫感染免疫反应中的效应细胞还是免疫调节剂?
Parasite Immunol. 2010 Jan;32(1):1-19. doi: 10.1111/j.1365-3024.2009.01147.x.
6
[Apoptosis, a protective mechanism for pathogens and their hosts].[细胞凋亡,病原体及其宿主的一种保护机制]
Wiad Parazytol. 2005;51(4):271-80.
7
Helminths at mucosal barriers--interaction with the immune system.黏膜屏障处的蠕虫——与免疫系统的相互作用
Adv Drug Deliv Rev. 2004 Apr 19;56(6):853-68. doi: 10.1016/j.addr.2003.10.033.
8
Th2 and Th1 Responses: Clear and Hidden Sides of Immunity Against Intestinal Helminths.Th2和Th1反应:肠道蠕虫免疫的显性与隐性方面
Trends Parasitol. 2017 Sep;33(9):678-693. doi: 10.1016/j.pt.2017.05.004. Epub 2017 May 26.
9
Immune and genetic aspects of asthma, allergy and parasitic worm infections: evolutionary links.哮喘、过敏及寄生虫感染的免疫与遗传因素:进化关联
Parasite Immunol. 2009 May;31(5):267-73. doi: 10.1111/j.1365-3024.2009.01104.x.
10
Immune modulation by helminthic infections: worms and viral infections.蠕虫感染引起的免疫调节:蠕虫与病毒感染
Parasite Immunol. 2006 Oct;28(10):483-96. doi: 10.1111/j.1365-3024.2006.00909.x.

引用本文的文献

1
Larval ascariasis elicits a prominent IgA and IgG1/2 antibody response to adult excretory/secretory antigens in pigs.仔猪蛔虫病会引发猪对成虫排泄/分泌抗原产生显著的IgA和IgG1/2抗体反应。
Front Immunol. 2025 Jul 30;16:1606128. doi: 10.3389/fimmu.2025.1606128. eCollection 2025.
2
Moonlighting on the Fasciola hepatica tegument: Enolase, a glycolytic enzyme, interacts with the extracellular matrix and fibrinolytic system of the host.肝片形吸虫表皮上的兼职现象:烯醇化酶,一种糖酵解酶,与宿主的细胞外基质和纤溶系统相互作用。
PLoS Negl Trop Dis. 2024 Aug 30;18(8):e0012069. doi: 10.1371/journal.pntd.0012069. eCollection 2024 Aug.
3
Th2-biased immune responses to body migrating Ascaris larvae in primary infection are associated with pathology but not protection.
在初次感染中,针对身体迁移的蛔虫幼虫的 Th2 偏向性免疫反应与病理学相关,但与保护无关。
Sci Rep. 2024 Jun 28;14(1):14919. doi: 10.1038/s41598-024-65281-0.
4
infection in juvenile pigs elicits a local Th2 response in a setting of ongoing Th1 expansion.在持续 Th1 扩增的背景下,幼年猪感染会引发局部 Th2 反应。
Front Immunol. 2024 May 10;15:1396446. doi: 10.3389/fimmu.2024.1396446. eCollection 2024.
5
Regulation of immune response against third-stage larvae by human genes.人体基因对第三期幼虫免疫反应的调控。
Front Immunol. 2023 Aug 3;14:1218965. doi: 10.3389/fimmu.2023.1218965. eCollection 2023.
6
Transcriptome Signatures of Atlantic Salmon-Resistant Phenotypes against Sea Lice Infestation Are Associated with Tissue Repair.大西洋鲑鱼抗海虱感染表型的转录组特征与组织修复有关。
Genes (Basel). 2023 Apr 27;14(5):986. doi: 10.3390/genes14050986.
7
The equine ascarids: resuscitating historic model organisms for modern purposes.马属蛔虫:为现代目的复兴历史模式生物。
Parasitol Res. 2022 Oct;121(10):2775-2791. doi: 10.1007/s00436-022-07627-z. Epub 2022 Aug 20.
8
Possible Roles of Specific Amino Acids in β-Tubulin Isotypes in the Growth and Maintenance of Neurons: Novel Insights From Cephalopod Mollusks.特定氨基酸在β-微管蛋白亚型对神经元生长和维持中的可能作用:来自头足类软体动物的新见解
Front Mol Neurosci. 2022 Apr 14;15:838393. doi: 10.3389/fnmol.2022.838393. eCollection 2022.
9
Human gnathostomiasis: a neglected food-borne zoonosis.人体颚口线虫病:一种被忽视的食源性人兽共患寄生虫病。
Parasit Vectors. 2020 Dec 9;13(1):616. doi: 10.1186/s13071-020-04494-4.
10
Host Immunity and Inflammation to Pulmonary Helminth Infections.宿主对肺部蠕虫感染的免疫与炎症反应
Front Immunol. 2020 Oct 20;11:594520. doi: 10.3389/fimmu.2020.594520. eCollection 2020.