胀果甘草根中的细胞毒性烯丙基反查耳酮。
Cytotoxic allyl retrochalcone from the roots of Glycyrrhiza inflata.
作者信息
Yoon Goo, Jung Young Do, Cheon Seung Hoon
机构信息
College of Pharmacy & Drug Development Research Institute, Chonnam National University, Gwangju 501-757, Korea.
出版信息
Chem Pharm Bull (Tokyo). 2005 Jun;53(6):694-5. doi: 10.1248/cpb.53.694.
PMID:15930786
Abstract
Two known retrochalcones, licochalcone A (1) and licochalcone C (2), and one new retrochalcone, licochalcone E (4) were isolated by cytotoxicity-guided fractionation from the roots of Glycyrrhiza inflata along with an ordinary chalcone, isoliquiritigenin (3). The structure of the new retrochalcone was elucidated through a spectroscopic analysis.
摘要
通过细胞毒性导向分级分离法，从胀果甘草根部分离出两种已知的反式查耳酮，光甘草定（1）和光甘草酮（2），以及一种新的反式查耳酮，光甘草新苷（4），同时还分离出一种普通查耳酮，异甘草素（3）。通过光谱分析阐明了新反式查耳酮的结构。
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