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胀果甘草根中的细胞毒性烯丙基反查耳酮。

Cytotoxic allyl retrochalcone from the roots of Glycyrrhiza inflata.

作者信息

Yoon Goo, Jung Young Do, Cheon Seung Hoon

机构信息

College of Pharmacy & Drug Development Research Institute, Chonnam National University, Gwangju 501-757, Korea.

出版信息

Chem Pharm Bull (Tokyo). 2005 Jun;53(6):694-5. doi: 10.1248/cpb.53.694.

DOI:10.1248/cpb.53.694
PMID:15930786
Abstract

Two known retrochalcones, licochalcone A (1) and licochalcone C (2), and one new retrochalcone, licochalcone E (4) were isolated by cytotoxicity-guided fractionation from the roots of Glycyrrhiza inflata along with an ordinary chalcone, isoliquiritigenin (3). The structure of the new retrochalcone was elucidated through a spectroscopic analysis.

摘要

通过细胞毒性导向分级分离法,从胀果甘草根部分离出两种已知的反式查耳酮,光甘草定(1)和光甘草酮(2),以及一种新的反式查耳酮,光甘草新苷(4),同时还分离出一种普通查耳酮,异甘草素(3)。通过光谱分析阐明了新反式查耳酮的结构。

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