Lech Teresa, Trela Franciszek
Institute of Forensic Research, Westerplatte 9, 31-033 Kraków, Poland.
Forensic Sci Int. 2005 Jul 16;151(2-3):273-7. doi: 10.1016/j.forsciint.2005.01.018.
Arsenic poisonings are still important in the field of toxicology, though they are not as frequent as about 20-30 years ago. In this paper, the arsenic concentrations in ante- and post-mortem materials, and also forensic and anatomo-pathological aspects in three cases of massive acute poisoning with arsenic(III) oxide (two of them with unexplained criminalistic background, in which arsenic was taken for amphetamine and one suicide), are presented. Ante-mortem blood and urine arsenic concentrations ranged from 2.3 to 6.7 microg/ml, respectively. Post-mortem tissue total arsenic concentrations were also detected in large concentrations. In case 3, the contents of the duodenum contained as much as 30.1% arsenic(III) oxide. The high concentrations of arsenic detected in blood and tissues in all presented cases are particularly noteworthy in that they are very rarely detected at these concentrations in fatal arsenic poisonings.
砷中毒在毒理学领域仍然很重要，尽管不像20到30年前那么频繁。本文介绍了三例三氧化二砷大规模急性中毒案例（其中两例背景不明，涉及将砷误当作苯丙胺，一例为自杀）的生前和死后材料中的砷浓度，以及法医和解剖病理学方面的情况。生前血液和尿液中的砷浓度分别为2.3至6.7微克/毫升。死后组织中的总砷浓度也被检测到处于高浓度。在案例3中，十二指肠内容物中含有高达30.1%的三氧化二砷。在所有呈现的案例中，血液和组织中检测到的高浓度砷尤其值得注意，因为在致命的砷中毒案例中，很少能检测到如此高的浓度。
