Rahman M Mukhlesur, Gray Alexander I
Phytochemistry Research Laboratories, Department of Pharmaceutical Sciences, University of Strathclyde, SIBS Building, 27 Taylor Street, Glasgow G4 ONR, Scotland, UK.
Phytochemistry. 2005 Jul;66(13):1601-6. doi: 10.1016/j.phytochem.2005.05.001.
A benzoisofuranone derivative, 3xi-(1xi-hydroxyethyl)-7-hydroxy-1-isobenzofuranone, and a dimeric carbazole alkaloid, 3,3'-[oxybis(methylene)]bis(9-methoxy-9H-carbazole), along with six known carbazole alkaloids and three known steroids were isolated from the stem bark of Murraya koenigii. The structures of these compounds were established unambiguously by UV, IR, MS and a series of 1D and 2D NMR analyses. The minimum inhibitory concentrations (MIC) of these compounds were found to be in the range 3.13-100 microg/ml.
从九里香的茎皮中分离出一种苯并异呋喃酮衍生物3xi-(1xi-羟乙基)-7-羟基-1-异苯并呋喃酮、一种二聚咔唑生物碱3,3'-[氧双(亚甲基)]双(9-甲氧基-9H-咔唑)，以及六种已知的咔唑生物碱和三种已知的甾体。通过紫外光谱、红外光谱、质谱以及一系列一维和二维核磁共振分析明确确定了这些化合物的结构。发现这些化合物的最低抑菌浓度（MIC）在3.13 - 100微克/毫升范围内。
