MacDonald S, Joffres M R, Stachenko S, Horlick L, Fodor G
Department of Community Health Sciences, Faculty of Medicine, University of Manitoba, Winnipeg.
CMAJ. 1992 Jun 1;146(11):2021-9.
To estimate the prevalence and distribution of the coexistence of major cardiovascular disease (CVD) risk factors among Canadian adults.
Population-based cross-sectional surveys.
Nine Canadian provinces, from 1986 to 1990.
A probability sample of 26,293 men and women, aged 18 to 74 years, was selected from provincial health insurance registries. For 20,582 of these participants, at least two blood pressure (BP) measurements were taken using a standardized technique. At a subsequent visit to a clinic, two additional BP readings, anthropometric measurements and a blood specimen for plasma lipid analysis were obtained.
The percentage distribution of subjects by number of major risk factors (smoking, high BP and elevated blood cholesterol level) and by concomitant factors (body mass index [BMI], ratio of waist to hip circumference [WHR], physical activity, diabetes, awareness of CVD risk factors and education).
Sixty-four percent of men and 63% of women had one or more of the major risk factors. Prevalence increased with age to reach 80% in men and 89% in women aged 65 to 74 years. Prevalence of two or three risk factors was highest among men in the 45-54 age group (34%) and in women in the 65-74 age group (37%). The most common associations were between smoking and high blood cholesterol level (10%) and between high BP and high blood cholesterol level (8%). Prevalence of high BP and elevated blood cholesterol, alone or in combination, increased with BMI and WHR. Smoking, elevated blood cholesterol, BMI and prevalence of one or more risk factors increased with lower level of education. Less than 48% of participants mentioned any single major risk factor as a cause of heart disease. Awareness was lowest in the group with fewest years of education.
The findings of this study call for an approach to reduce CVD that stresses collaboration of the different health sectors to reach both the population as a whole and the individuals at high risk.
评估加拿大成年人中主要心血管疾病(CVD)风险因素共存的患病率及分布情况。
基于人群的横断面调查。
1986年至1990年期间的加拿大九个省份。
从省级医疗保险登记处选取了26293名年龄在18至74岁之间的男性和女性作为概率样本。其中20582名参与者使用标准化技术进行了至少两次血压(BP)测量。在随后的诊所就诊时,又获得了另外两次血压读数、人体测量数据以及一份用于血浆脂质分析的血样。
按主要风险因素数量(吸烟、高血压和高胆固醇血症)以及伴随因素(体重指数[BMI]、腰臀比[WHR]、身体活动、糖尿病、对CVD风险因素的认知以及教育程度)对受试者进行百分比分布统计。
64%的男性和63%的女性有一个或多个主要风险因素。患病率随年龄增长而升高,在65至74岁的男性中达到80%,在女性中达到89%。两个或三个风险因素的患病率在45至54岁的男性中最高(34%),在65至74岁的女性中最高(37%)。最常见的关联是吸烟与高胆固醇血症之间(10%)以及高血压与高胆固醇血症之间(8%)。高血压和高胆固醇血症单独或合并出现的患病率随BMI和WHR升高而增加。吸烟、高胆固醇血症、BMI以及一个或多个风险因素的患病率随教育程度降低而增加。不到48%的参与者提及任何单一主要风险因素是心脏病的病因。在受教育年限最少的人群中,认知程度最低。
本研究结果呼吁采取一种减少心血管疾病的方法,强调不同卫生部门之间的合作,以覆盖整个群体以及高危个体。