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心血管疾病的人群风险:明尼苏达心脏调查

Population risk of cardiovascular disease: the Minnesota Heart Survey.

作者信息

Luepker R V, Jacobs D R, Gillum R F, Folsom A R, Prineas R J, Blackburn H

出版信息

J Chronic Dis. 1985;38(8):671-82. doi: 10.1016/0021-9681(85)90021-9.

Abstract

A decline in age-adjusted ischemic cardiovascular disease mortality has been observed in the United States during the past two decades. Among the leading explanatory hypotheses is improvement in the major known risk factors for heart attack and stroke in the general population, specifically hypertension, smoking, and lipid levels. To better understand risk factor trends, the Minnesota Heart Survey (MHS) began systematic risk factor surveys of the Minneapolis-St Paul population in 1980, (population 1.99 million). The metropolitan area was divided into 704 subareas (clusters) of approx. 1000 households each, utilizing geographic boundaries. In a two-stage cluster sampling technique, 40 subareas were randomly chosen and mapped. Approximately 8.75% of households were chosen from each subarea and selected residents age 25-74 years invited to participate. A total 4451 individuals participated in 1980-82. The response rate for a home interview was 81.9 and 84.4% for a subsequent survey center visit, producing an overall response of 69.1%. The age and sociodemographic characteristics of the survey participants were similar to those found in the 1980 census. The prevalence of hypertension was 18.3% in this population with 76.0% taking medications and 65.0% controlled. Total cholesterol and HDL-cholesterol levels demonstrated age and sex differences similar to those reported elsewhere. Current smoking of cigarettes was equally prevalent in men (34.5%) and women (33.5%) although more men were former smokers (35.2 vs 20.6%). Comparison of the MHS with the National HANES II data (1976-80) indicates lower regular cigarette smoking among Minnesota males, with similar rates in females. Minnesota residents had better control of high blood pressure.

摘要

在过去二十年中,美国经年龄调整的缺血性心血管疾病死亡率呈下降趋势。主要的解释性假设之一是,普通人群中心脏病发作和中风的主要已知风险因素有所改善,特别是高血压、吸烟和血脂水平。为了更好地了解风险因素的趋势,明尼苏达心脏调查(MHS)于1980年开始对明尼阿波利斯 - 圣保罗人群(人口199万)进行系统的风险因素调查。利用地理边界,将大都市区划分为约704个分区(集群),每个分区约有1000户家庭。采用两阶段整群抽样技术,随机选择并绘制了40个分区。从每个分区中选取约8.75%的家庭,并邀请选定的25 - 74岁居民参与。1980 - 1982年共有4451人参与。家庭访谈的回复率为81.9%,后续调查中心访问的回复率为84.4%,总体回复率为69.1%。调查参与者的年龄和社会人口特征与1980年人口普查中的特征相似。该人群中高血压患病率为18.3%,76.0%的人正在服药,65.0%的人血压得到控制。总胆固醇和高密度脂蛋白胆固醇水平呈现出与其他地方报道相似的年龄和性别差异。目前吸烟在男性(34.5%)和女性(33.5%)中同样普遍,不过 former smokers 更多的是男性(35.2%对20.6%)。将MHS与国家健康与营养检查调查II(HANES II)数据(1976 - 1980年)进行比较表明,明尼苏达州男性中经常吸烟的比例较低,女性比例相似。明尼苏达州居民对高血压的控制更好。 (注:原文中“former smokers”直译为“以前的吸烟者”,结合语境这里可能是想说“曾经吸烟但现在已戒烟的人”,翻译为“已戒烟者”更符合中文表达习惯,但按照要求未添加解释。)

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