Kutschke Amy, de Jonge Boudewijn L M
Infection Discovery, Cancer and Infection Research Area, AstraZeneca R&D Boston, 35 Gatehouse Drive, Waltham, Massachusetts 02451, USA.
Antimicrob Agents Chemother. 2005 Jul;49(7):3009-10. doi: 10.1128/AAC.49.7.3009-3010.2005.
Susceptibility testing with a variety of structurally unrelated compounds showed that hefC in Helicobacter pylori is involved in multidrug efflux. This efflux was shown to depend on the proton motive force, as demonstrated by ethidium bromide accumulation experiments. Thus, H. pylori contains an active multidrug efflux mechanism.
对多种结构不相关化合物进行的药敏试验表明，幽门螺杆菌中的hefC参与多药外排。如溴化乙锭积累实验所示，这种外排依赖于质子动力。因此，幽门螺杆菌含有一种活跃的多药外排机制。
