肠炎沙门氏菌婴儿亚种中bla(CTX-M-2)基因的转录分析。
Transcriptional analysis of the bla(CTX-M-2) gene in Salmonella enterica serovar Infantis.
作者信息
Di Conza José A, Gutkind Gabriel O, Mollerach Marta E, Ayala Juan A
机构信息
Cátedra de Microbiología, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Argentina.
出版信息
Antimicrob Agents Chemother. 2005 Jul;49(7):3014-7. doi: 10.1128/AAC.49.7.3014-3017.2005.
Abstract
Transcriptional organization of bla(CTX-M-2) present in a multiresistance plasmid of Salmonella enterica serovar Infantis suggests the presence of more than one promoter involved in the expression of the beta-lactamase gene. At least two bla(CTX-M-2)-specific mRNAs (near to 1 kb and 5 kb) were evidenced. Two +1 signals were detected at -22 bp and -59 bp of bla(CTX-M-2) defining two putative promoters.
摘要
存在于肠炎沙门氏菌婴儿亚种多重耐药质粒中的bla(CTX-M-2)转录组织表明，β-内酰胺酶基因表达涉及不止一个启动子。至少证实了两种bla(CTX-M-2)特异性mRNA（接近1 kb和5 kb）。在bla(CTX-M-2)的-22 bp和-59 bp处检测到两个+1信号，确定了两个推定启动子。
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