Yoshiya I, Shimada Y, Tanaka K
J Appl Physiol Respir Environ Exerc Physiol. 1979 Nov;47(5):1131-5. doi: 10.1152/jappl.1979.47.5.1131.
A hot-wire flowmeter was evaluated for clinical applicability. 1) Calibration with a syringe could be done if emptying duration was 1-15 s. 2) Outputs linearly decreased with decreasing concentration of N2 in O2. Outputs with CO2 in O2 and N2O in O2 represented nonlinear convex relationships with varying concentrations of CO2 and N2O. Correction for each gas mixture to be measured is required. 3) Outputs linearly decreased with decreasing barometric pressure. 4) Stability assessed with a piston respirator was excellent (within +/- 2% of syringe volume) after 15 min warmup time. However, daily calibrations are recommended in clinical situations. 5) Nebulization, if not excessive, was acceptable if the expired gas was measured at the mouth. 6) Hot-wire burning, which occurred when it was partially in contact with materials whose specific heat differed with air, was successfully protected with a simple shutoff circuit. 7) The possibility of producing nitrogen oxides by the catalytic action of the platinum hot-wire was denied by colorimetric determination. Interchangeability and sterilizability of transducers and improved mechanical strength with platinum-rhodium alloy are also discussed.
对一种热线流量计的临床适用性进行了评估。1)如果排空持续时间为1 - 15秒,则可以使用注射器进行校准。2)随着氧气中氮气浓度的降低,输出呈线性下降。氧气中二氧化碳和氧气中氧化亚氮的输出与二氧化碳和氧化亚氮的不同浓度呈现非线性凸关系。需要对每种待测气体混合物进行校正。3)随着气压的降低,输出呈线性下降。4)在15分钟预热时间后,用活塞呼吸器评估的稳定性极佳(在注射器体积的+/- 2%范围内)。然而,在临床情况下建议进行每日校准。5)如果雾化不过度,在口腔测量呼出气体时是可以接受的。6)当热线与比热与空气不同的材料部分接触时发生的热线燃烧,通过一个简单的切断电路成功得到了保护。7)通过比色测定否定了铂热线催化作用产生氮氧化物的可能性。还讨论了传感器的互换性和可消毒性以及铂铑合金提高的机械强度。