Fedele Luigi, Bianchi Stefano, Zanconato Giovanni, Berlanda Nicola, Borruto Franco, Frontino Giada
Clinica Ostetrico-Ginecologica dell'Università di Milano, Ospedale San Paolo, Milano, Italy.
Am J Obstet Gynecol. 2005 Jul;193(1):114-7. doi: 10.1016/j.ajog.2004.12.085.
The purpose of this study was to compare the outcome of standard extrafascial hysterectomy and tailored radical hysterectomy as a definitive treatment of recurrent deep endometriosis.
This was a descriptive study that comprised 38 patients who underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy between 1989 and 2002 for symptomatic recurrences of deep endometriosis, after>or=1 previous surgical procedures and ovarian suppressive medical treatments. After the operation, all of the patients were given transdermal estradiol. The minimum follow-up time was 24 months.
Twenty-six patients underwent standard extra-fascial hysterectomy (group A), and 12 patients underwent modified radical hysterectomy that included the removal of all deeply infiltrating endometriotic lesions (group B). The recurrence of pain caused by endometriosis occurred in 8 women (31%) of group A and in no patients of group B.
Definitive surgery for deep endometriosis should include the removal of the uterus, adnexa, and all surgically accessible deep lesions. As a consequence, the surgeon must be familiar with radical pelvic surgery.
本研究旨在比较标准筋膜外子宫切除术和改良根治性子宫切除术作为复发性深部子宫内膜异位症的确定性治疗方法的效果。
这是一项描述性研究,纳入了1989年至2002年间因深部子宫内膜异位症症状复发而接受全腹子宫切除术和双侧输卵管卵巢切除术的38例患者,这些患者此前至少接受过1次手术治疗和卵巢抑制性药物治疗。术后,所有患者均接受经皮雌二醇治疗。最短随访时间为24个月。
26例患者接受标准筋膜外子宫切除术(A组),12例患者接受改良根治性子宫切除术,包括切除所有深度浸润的子宫内膜异位病变(B组)。A组8名女性(31%)出现子宫内膜异位症引起的疼痛复发,B组无患者出现复发。
深部子宫内膜异位症的确定性手术应包括切除子宫、附件和所有手术可及的深部病变。因此,外科医生必须熟悉根治性盆腔手术。