Jain K K
Jain PharmaBiotech, Blaesiring 7, CH-4057 Basel, Switzerland.
Technol Cancer Res Treat. 2005 Aug;4(4):407-16. doi: 10.1177/153303460500400408.
Nanobiotechnologies have been applied to improve drug delivery and to overcome some of the problems of drug delivery in cancer. These can be classified into many categories that include use of various nanoparticles, nanoencapsulation, targeted delivery to tumors of various organs, and combination with other methods of treatment of cancer such as radiotherapy. Nanoparticles are also used for gene therapy for cancer. Some of the technologies enable combination of diagnostics with therapeutics which will be important for the personalized management of cancer. Some of the limitations of these technologies and prospects for future development are discussed.
纳米生物技术已被应用于改善药物递送，并克服癌症药物递送中的一些问题。这些可分为许多类别，包括使用各种纳米颗粒、纳米封装、靶向递送至各个器官的肿瘤，以及与其他癌症治疗方法（如放射疗法）相结合。纳米颗粒也用于癌症的基因治疗。一些技术能够实现诊断与治疗的结合，这对癌症的个性化管理至关重要。本文讨论了这些技术的一些局限性以及未来发展前景。
