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一项关于自闭症和多种复杂发育障碍儿童形式思维障碍的对照研究。

A controlled study of formal thought disorder in children with autism and multiple complex developmental disorders.

作者信息

van der Gaag Rutger J, Caplan Rochelle, van Engeland Herman, Loman F, Buitelaar Jan K

机构信息

University Medical Centre St. Radboud Nijmegen-Academic Centre for Child and Adolescent Psychiatry, Nijmegen, The Netherlands.

出版信息

J Child Adolesc Psychopharmacol. 2005 Jun;15(3):465-76. doi: 10.1089/cap.2005.15.465.

Abstract

UNLABELLED

Along with well-defined categories in classification systems (e.g., autistic disorders and attention-deficit/hyperactivity disorder (ADHD)), practitioners are confronted with many children showing mixed forms of developmental psychopathology. These clusters of symptoms are on the borderlines of more defined categories. The late Donald Cohen proposed heuristic criteria to study a group defined by impaired social sensitivity, impaired regulation of affect, and thinking disorders under the name multiple complex developmental disorders (MCDD). Although these children meet criteria for pervasive developmental disorder--not otherwise specified (PDD-NOS), they have additional important clinical features, such as thought disorder. After highlighting similarities and differences between MCDD and comparable groups (e.g., multidimensionally impaired children), this paper presents the findings of a study comparing formal thought disorder scores in children with MCDD to children with autism spectrum diagnoses, such as autistic disorder (AD), and to children with nonspectrum diagnoses, such as ADHD and anxiety disorders.

METHODS

Videotaped speech samples of four groups of high-functioning, latency-aged children with MCDD, AD, ADHD, and anxiety disorders were compared to a control group of normal children using the Kiddie Formal Thought Disorder Rating Scale (K-FTDS).

RESULTS

High formal thought disorder scores were found both in the AD and MCDD groups, low rates in the ADHD groups, and no thought disorder in the anxiety disorder and normal control groups. The severity of formal thought disorder was related to verbal IQ scores within the AD and MCDD groups.

CONCLUSION

High formal thought scores in children with complex developmental disorders, such as AD and MCDD, appear to reflect impaired communication skills rather than early signs of psychosis.

摘要

未标注

在分类系统中有明确的类别(例如,自闭症谱系障碍和注意力缺陷多动障碍(ADHD)),从业者还面临着许多表现出发育性精神病理学混合形式的儿童。这些症状群处于更明确类别的边界。已故的唐纳德·科恩提出了启发式标准,用于研究一组以社会敏感性受损、情感调节受损和思维障碍为特征的群体,名为多重复杂发育障碍(MCDD)。尽管这些儿童符合未特定的广泛性发育障碍(PDD-NOS)的标准,但他们还有其他重要的临床特征,如思维障碍。在强调MCDD与可比群体(例如,多维度受损儿童)之间的异同之后,本文展示了一项研究的结果,该研究比较了MCDD儿童与自闭症谱系诊断儿童(如自闭症障碍(AD))以及非谱系诊断儿童(如ADHD和焦虑症)的形式思维障碍得分。

方法

使用儿童形式思维障碍评定量表(K-FTDS),将四组高功能、学龄期的患有MCDD、AD、ADHD和焦虑症的儿童的录像言语样本与一组正常儿童的样本进行比较。

结果

在AD组和MCDD组中发现形式思维障碍得分较高,在ADHD组中得分较低,在焦虑症组和正常对照组中未发现思维障碍。AD组和MCDD组中形式思维障碍的严重程度与言语智商得分相关。

结论

患有复杂发育障碍(如AD和MCDD)的儿童中较高的形式思维得分似乎反映了沟通技能受损,而非精神病的早期迹象。

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