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圣犹达医疗Symmetry主动脉连接器的早期临床结果。

Early clinical results of St. Jude Medical Symmetry aortic connector.

作者信息

Toyama Masashi, Usui Akihiko, Abe Tomonobu, Yoshikawa Masaharu, Akita Toshiaki, Ueda Yuichi

机构信息

Department of Cardiothoracic Surgery, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya 466-8550, Japan.

出版信息

J Artif Organs. 2005;8(2):95-9. doi: 10.1007/s10047-005-0293-0.

Abstract

An automated anastomosis device named St. Jude Medical symmetry aortic connector has been used worldwide for off-pump coronary artery bypass grafting. However, early graft obstruction was recently reported, and its predictors should be clarified. From April 2002 to March 2004, 38 patients in our institution underwent off-pump coronary artery bypass grafting using the St. Jude Medical Symmetry aortic connector for saphenous vein graft (SVG) procedures; measurement of intraoperative graft flow and postoperative coronary angiography was performed. Early SVG events occurred in 9 (24%) patients: 8 occlusion cases and 1 case of stenosis. Predictors of early SVG events were assessed from a comparative study. Univariate logistic regression identified hyperlipidemia as the only significant predictor of early SVG events (P = 0.02, odds ratio 7.78). Lower SVG flow rate and poor ejection fraction did not show statistical significance (P = 0.09, odds ratio 1.09 and P = 0.09, odds ratio 0.96). The SVG event rate was much higher for the left circumflex branch compared with other locations (31% vs. 9%, P = 0.03) and decreased with increasing aortic connector size (small, 32%; median, 14%; large, 0%). Multivariate analysis did not identify a predictor of SVG events. The aortic connector is associated with a high incidence of early SVG events. Patients should be cautiously selected and the procedure should not be used for left anterior descending coronary artery or culprit lesions.

摘要

一种名为圣犹达医疗对称主动脉连接器的自动吻合装置已在全球范围内用于非体外循环冠状动脉旁路移植术。然而,最近有早期移植物阻塞的报道,其预测因素应予以明确。从2002年4月至2004年3月,我院38例患者使用圣犹达医疗对称主动脉连接器进行非体外循环冠状动脉旁路移植术以行大隐静脉移植(SVG)手术;术中对移植物血流进行了测量,并进行了术后冠状动脉造影。9例(24%)患者发生早期SVG事件:8例阻塞病例和1例狭窄病例。通过比较研究评估早期SVG事件的预测因素。单因素逻辑回归分析确定高脂血症是早期SVG事件的唯一显著预测因素(P = 0.02,比值比7.78)。较低的SVG流速和较差的射血分数未显示统计学意义(P = 0.09,比值比1.09和P = 0.09,比值比0.96)。与其他部位相比,左旋支的SVG事件发生率要高得多(31%对9%,P = 0.03),并且随着主动脉连接器尺寸的增加而降低(小尺寸,32%;中等尺寸,14%;大尺寸,0%)。多因素分析未确定SVG事件的预测因素。主动脉连接器与早期SVG事件的高发生率相关。应谨慎选择患者,该手术不适用于左前降支冠状动脉或罪犯病变。

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