Murphy C C, Hughes E H, Frost N A, Dick A D
Division of Ophthalmology, University of Bristol, Bristol BS1 2LX, UK.
Br J Ophthalmol. 2005 Sep;89(9):1161-5. doi: 10.1136/bjo.2005.067421.
To assess visual function, vision related quality of life (VR-QOL), and general health related quality of life (HR-QOL) in intermediate uveitis (IU).
VR-QOL and HR-QOL were evaluated in 42 patients with IU using the VCM1 and SF-36 questionnaires, respectively. LogMAR visual acuity (VA), Pelli-Robson contrast sensitivity (CS), Farnsworth-Munsell 100 hue colour vision (CV), and Estermann visual field (VF) were recorded monocularly and binocularly.
Median (interquartile range) visual acuity (VA) and CS of 72 affected eyes were 0.1 (0.015-0.3) and 1.55 (1.35-1.65), respectively. 9.5% of patients had a VCM1 score of more than 2.0, indicating "more than a little" concern over vision. Worse eye VA (p=0.045) and CS (p=0.042) were predictive of a VCM1 score of more than 2.0 independently of age, sex, uveitis duration, laterality and activity, systemic uveitis therapy, and medical co-morbidity. The physical and mental component summary scores of the SF-36 were significantly worse in those who reported significant impairment of vision on the VCM1 than those who did not.
The majority of patients with IU maintain good visual function and quality of life. VR-QOL impairment in IU correlates with vision in the worse eye and is associated with impaired HR-QOL.
评估中间葡萄膜炎(IU)患者的视觉功能、视力相关生活质量(VR-QOL)和总体健康相关生活质量(HR-QOL)。
分别使用VCM1问卷和SF-36问卷对42例IU患者的VR-QOL和HR-QOL进行评估。单眼和双眼记录LogMAR视力(VA)、佩利-罗布森对比敏感度(CS)、法恩斯沃思-芒塞尔100色觉(CV)和埃斯特曼视野(VF)。
72只患眼的中位(四分位间距)视力(VA)和CS分别为0.1(0.015 - 0.3)和1.55(1.