Department of Zoology, Government College University, Faisalabad 38000, Pakistan.
Institute of Microbiology, Government College University, Faisalabad 38000, Pakistan.
Molecules. 2023 Apr 14;28(8):3469. doi: 10.3390/molecules28083469.
As is well known, plant products have been increasingly utilized in the pharmaceutical industry in recent years. By combining conventional techniques and modern methodology, the future of phytomedicines appears promising. (patchouli) is an important herb used frequently in the fragrance industries and has various therapeutic benefits. Traditional medicine has long used the essential oil of patchouli () as a flavoring agent recognized by the FDA. This is a gold mine for battling pathogens in China and India. In recent years, this plant has seen a significant surge in use, and approximately 90% of the world's patchouli oil is produced by Indonesia. In traditional therapies, it is used for the treatment of colds, fever, vomiting, headaches, and stomachaches. Patchouli oil is used in curing many diseases and in aromatherapy to treat depression and stress, soothe nerves, regulate appetite, and enhance sexual attraction. More than 140 substances, including alcohols, terpenoids, flavonoids, organic acids, phytosterols, lignins, aldehydes, alkaloids, and glycosides, have been identified in . Pachypodol (C18H16O7) is an important bioactive compound found in Pachypodol (C18H16O7) and many other biologically essential chemicals have been separated from the leaves of and many other medicinally significant plants using repeated column chromatography on silica gel. Pachypodol's bioactive potential has been shown by a variety of assays and methodologies. It has been found to have a number of biological activities, including anti-inflammatory, antioxidant, anti-mutagenic, antimicrobial, antidepressant, anticancer, antiemetic, antiviral, and cytotoxic ones. The current study, which is based on the currently available scientific literature, intends to close the knowledge gap regarding the pharmacological effects of patchouli essential oil and pachypodol, a key bioactive molecule found in this plant.
众所周知，近年来，植物产品在制药行业中的应用日益增多。通过结合传统技术和现代方法，植物药的未来前景广阔。（广藿香）是一种在香料工业中经常使用的重要草药，具有多种治疗功效。传统医学长期以来一直将广藿香精油（）用作 FDA 认可的调味剂。这是中国和印度对抗病原体的宝库。近年来，这种植物的使用量显著增加，世界上约 90%的广藿香油由印度尼西亚生产。在传统疗法中，它用于治疗感冒、发烧、呕吐、头痛和胃痛。广藿香油用于治疗许多疾病和芳香疗法，以治疗抑郁和压力、舒缓神经、调节食欲和增强性吸引力。已在中鉴定出包括醇、萜类、类黄酮、有机酸、植物甾醇、木质素、醛、生物碱和糖苷在内的 140 多种物质。（C18H16O7）是广藿香中的一种重要生物活性化合物。已经从和许多其他药用植物的叶子中分离出（C18H16O7）和许多其他生物必需的化学物质，方法是在硅胶上反复进行柱层析。多种测定和方法已经证明了 pachypodol 的生物活性潜能。已经发现它具有多种生物活性，包括抗炎、抗氧化、抗突变、抗菌、抗抑郁、抗癌、止吐、抗病毒和细胞毒性。本研究基于目前可获得的科学文献，旨在填补有关广藿香精油和 pachypodol 的药理作用的知识空白，pachypodol 是这种植物中的一种关键生物活性分子。
