Effect of ghrelin on activities of some lysosomal hydrolases in rabbits.

作者信息

Witek Bozena, Ochwanowska Ewa, Rafay Jan, Kolataj Adam, Chrenek Peter, Suvegova Karin, Jurcik Rastislav, Sirotkin Alexander, Darlak Krzysztof

机构信息

Department of Genetics, Institute of Biology, Swietokrzyska Academy, Kielce, Poland.

出版信息

Neuro Endocrinol Lett. 2005 Aug;26(4):397-400.

OBJECTIVES

Observing the changes of activity of some lysosomal enzymes in blood serum of female rabbits subjected to injection of 10 microg of ghrelin/kg of body weight.

METHODS

In the blood serum the activity of cathepsins D and L, alanine aminopeptidase, acid phosphatase, lysosomal lipase and lysosomal esterase was determined.

RESULTS

As a result of ghrelin injection the activity of all the enzymes examined in blood serum increased markedly.

CONCLUSION

Changes of lysosomal enzymes activities in the blood serum caused by the effects of ghrelin should be regarded as the response of the lysosomal system.