Hsu Cheng-Chen, Ho Min-Chen, Lin Li-Chin, Su Borcherng, Hsu Mei-Chich
Graduate Institute of Sports Science, National College of Physical Education and Sports, Taoyuan County, Taiwan, China.
World J Gastroenterol. 2005 Sep 14;11(34):5327-31. doi: 10.3748/wjg.v11.i34.5327.
To investigate whether American ginseng (AG, Panax quinquefolium) supplementation was able to improve endurance exercise performance.
Thirteen physically active male college students were divided into two groups (AG or placebo) and received supplementation for 4 wk, before the exhaustive running exercise. Treadmill speed was increased to a pace equivalent to 80% VO2max of the subject. A 4-wk washout period followed before the subjects crossed over and received the alternate supplement for the next 4 wk. They then completed a second exhaustive running exercise. The physiological variables that were examined included time to exhaustion and oxygen pulse. Moreover, the plasma creatine kinase (CK) and lactate were measured prior to the exercise, at 15 and 30 min during exercise, immediately after exercise, and 20, 40, 60, and 120 min after exercise.
The major finding of this investigation was that the production plasma CK during the exercise significantly decreased for group AG than for group P. Secondary physiological finding was that 80% VO2max running was not improved over a 4-wk AG supplementation regimen.
Supplementation with AG for 4 wk prior to an exhaustive aerobic treadmill running reduced the leakage of CK during exercise, but did not enhance aerobic work capacity. The reduction of plasma CK may be due to the fact that AG is effective for the decrease of skeletal muscle cell membrane damage, induced by exercise during the high-intensity treadmill run.
研究补充西洋参（AG，西洋参）是否能够提高耐力运动表现。
13名身体活跃的男性大学生被分为两组（AG组或安慰剂组），并在进行力竭性跑步运动前接受4周的补充剂。跑步机速度增加至相当于受试者最大摄氧量（VO2max）80%的配速。在受试者交叉并接受替代补充剂进行接下来的4周之前，有一个4周的洗脱期。然后他们完成第二次力竭性跑步运动。所检测的生理变量包括力竭时间和氧脉搏。此外，在运动前、运动期间15分钟和30分钟、运动后即刻以及运动后20、40、60和120分钟测量血浆肌酸激酶（CK）和乳酸。
本研究的主要发现是，与P组相比，AG组在运动期间血浆CK的产生显著降低。次要生理发现是，在4周的AG补充方案中，80%VO2max的跑步表现没有得到改善。
在进行力竭性有氧跑步机跑步前4周补充AG可减少运动期间CK的泄漏，但并未提高有氧工作能力。血浆CK的降低可能是由于AG对高强度跑步机跑步运动期间诱导的骨骼肌细胞膜损伤的减轻有效。
