Bertoldi C, Pradelli J M, Consolo U, Zaffe D
Department of Neurosciences, Head-Neck and Rehabilitation, Section of Dentistry and Maxillofacial Surgery, University of Modena and Reggio Emilia, Italy.
J Mater Sci Mater Med. 2005 Sep;16(9):857-61. doi: 10.1007/s10856-005-3575-4.
Vitallium appliances and surrounding tissues were investigated to evaluate the release and accumulation of elements. Four microplates, sixteen screws and surrounding tissues were removed from three patients presenting inflammation 4 to 6 years after surgery and were submitted to SEM and X-ray microprobe analysis. Histology was performed on paraffin or PMMA sections of tissues.A continuous release of elements from metallic appliances into soft tissues was observed. Cobalt, chromium, and nickel were detected in soft and boney tissues in close proximity to the appliance. Aluminium, as a component of screw coatings, accumulated in soft tissues, and a remarkable amount of aluminium was detected in the dense lamella of lamellar bone. The results suggest that coatings containing aluminium should be avoided and the time these appliances are allowed to remain in patients should be shortened. Further studies on element release and the fate of aluminium in bone are warranted.
对维他灵矫治器及其周围组织进行了研究，以评估元素的释放和积累情况。从三名术后4至6年出现炎症的患者身上取出四个微型板、十六颗螺钉及其周围组织，进行扫描电子显微镜（SEM）和X射线微探针分析。对组织的石蜡或聚甲基丙烯酸甲酯（PMMA）切片进行了组织学检查。观察到金属矫治器中的元素持续释放到软组织中。在矫治器附近的软组织和骨组织中检测到了钴、铬和镍。作为螺钉涂层成分的铝在软组织中积累，并且在板层骨的致密板层中检测到了大量的铝。结果表明应避免使用含铝涂层，并且应缩短这些矫治器在患者体内的留存时间。有必要对元素释放以及铝在骨骼中的归宿进行进一步研究。
