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Karydakis手术与中线切除术治疗藏毛窦疾病的比较。

Comparison of Karydakis versus midline excision for treatment of pilonidal sinus disease.

作者信息

Morden Peter, Drongowski Robert A, Geiger James D, Hirschl Ronald B, Teitelbaum Daniel H

机构信息

Section of Pediatric Surgery, C.S. Mott Children's Hospital, University of Michigan Medical Center, Ann Arbor, MI 48109-0245, USA.

出版信息

Pediatr Surg Int. 2005 Oct;21(10):793-6. doi: 10.1007/s00383-005-1543-1. Epub 2005 Oct 21.

Abstract

Pilonidal sinus disease is associated with a high rate of recurrence and complications. The Karydakis (KAR) method, whereby an asymmetric subcutaneous flap obliterates the anal crease, has been shown to be effective in adults. The goal of this study is to assess the efficacy of the KAR procedure in the operative treatment of children with pilonidal sinus disease compared to those treated via a midline excision (ME). Sixty-eight cases of pediatric pilonidal sinus excision were reviewed over the past 10 years. Data abstracted included surgical approach, complication rate and recurrence rate. Student's t-test or the Chi square test was used for statistical analysis, with P < 0.05 being considered significant. An ME was performed in 44 patients; the KAR method was used in 24 patients. Mean age at diagnosis was 14.4 +/- 4.2 years for the ME group compared to 15.7 +/- 4.3 years for the KAR patients (P = 0.18). Mean operative time was significantly longer with the KAR method (58.7 +/- 25.6 min) compared to 46.3 +/- 18.6 for the primary ME (P = 0.04). Despite the increased operative dissection, there was no difference (P = 0.42) in early post-operative complication rates between groups (25% in the KAR group compared to 34.8% in the ME group). Initial drainage of an abscess had no significant effect upon the recurrence/complication rate in either group. Recurrence rate alone was lower in patients operated on via the KAR approach 0% versus 11.0% using the ME (P = 0.153). Recurrence and complication rates were lower for those patients with a pilonidal sinus treated by the KAR method compared to the ME, but the results did not reach significance. In conclusion, this study does show a potential benefit for children treated with the KAR method for pilonidal sinus. This study mimics the data obtained in adult patients and suggests that a larger study is likely to achieve significance.

摘要

藏毛窦疾病与高复发率及并发症相关。卡里达基斯(KAR)方法,即通过一个不对称的皮下皮瓣消除肛门皱襞,已被证明在成人中有效。本研究的目的是评估KAR手术在小儿藏毛窦疾病手术治疗中的疗效,并与经中线切除(ME)治疗的患儿进行比较。回顾了过去10年里68例小儿藏毛窦切除病例。提取的数据包括手术方式、并发症发生率和复发率。采用学生t检验或卡方检验进行统计分析,P<0.05被认为具有统计学意义。44例患者接受了ME手术;24例患者采用了KAR方法。ME组诊断时的平均年龄为14.4±4.2岁,而KAR组患者为15.7±4.3岁(P = 0.18)。与初次ME手术的46.3±18.6分钟相比,KAR方法的平均手术时间明显更长(58.7±25.6分钟)(P = 0.04)。尽管手术剥离范围增加,但两组术后早期并发症发生率无差异(P = 0.42)(KAR组为25%,ME组为34.8%)。脓肿的初始引流对两组的复发/并发症发生率均无显著影响。单独来看,采用KAR手术方法的患者复发率较低,为0%,而采用ME手术的复发率为11.0%(P = 0.153)。与ME相比,采用KAR方法治疗藏毛窦的患者复发率和并发症发生率较低,但结果未达到统计学意义。总之,本研究确实显示了KAR方法治疗小儿藏毛窦具有潜在益处。本研究模仿了在成年患者中获得的数据,并表明更大规模的研究可能会得出有统计学意义的结果。

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