Einollahi B, Lessan-Pezeshki M, Simforoosh N, Nafar M, Pour-Reza-Gholi F, Firouzan A, Khatami M R, Nourbala M H, Pourfarzini V
Kidney Transplant Department, Baqiyatallah Hospital, Baqiyatallah University of Medical Sciences, Tehran, Iran.
Transplant Proc. 2005 Sep;37(7):3004-5. doi: 10.1016/j.transproceed.2005.08.032.
Fasting during the holy month of Ramadan is a religious duty for all healthy adult Muslims. They are only allowed to eat and drink between sunset and dawn. This study was designed to find the effect of Ramadan fasting on allograft function. We prospectively studied 19 kidney transplant recipients who voluntarily chose to fast during Ramadan versus 20 matched recipients, who had not fasted for 3 consecutive years. Data were recorded before, during, and after the fasting month. The mean posttransplant periods in the fasting and control groups were 52.6 +/- 30.3 and 56.6 +/- 30.0 months, respectively. A statistical analysis showed no significant changes in serum creatinine concentrations before and after Ramadan 1.07 +/- 0.24 versus 1.08 +/- 0.22 mg/dL (P > .05) and 1.00 +/- 0.24 versus 1.03 +/- 0.28 mg/dL (P > .05) in fasting and control groups, respectively. The results did not show any adverse effects of fasting in recipients with stable renal function. In conclusion, our study suggests that fasting during the month of Ramadan is safe and has no significant harmful effects on kidney transplant recipients with normal renal function.
在斋月期间禁食是所有健康成年穆斯林的宗教义务。他们只被允许在日落后至黎明前进食和饮水。本研究旨在探讨斋月禁食对同种异体移植功能的影响。我们前瞻性地研究了19名自愿选择在斋月期间禁食的肾移植受者，并与20名连续3年未禁食的匹配受者进行对比。在禁食月之前、期间和之后记录数据。禁食组和对照组的移植后平均时间分别为52.6±30.3个月和56.6±30.0个月。统计分析显示，禁食组和对照组在斋月前后血清肌酐浓度无显著变化，分别为1.07±0.24与1.08±0.22mg/dL（P>.05）以及1.00±0.24与1.03±0.28mg/dL（P>.05）。结果未显示禁食对肾功能稳定的受者有任何不良影响。总之，我们的研究表明，斋月期间禁食是安全的，对肾功能正常的肾移植受者没有显著有害影响。
