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瑞士反刍动物瘟病毒的遗传异质性

Genetic heterogeneity of pestiviruses of ruminants in Switzerland.

作者信息

Stalder H P, Meier Ph, Pfaffen G, Wageck-Canal C, Rüfenacht J, Schaller P, Bachofen C, Marti S, Vogt H R, Peterhans E

机构信息

Institute of Veterinary Virology, University of Bern, Länggass-Str. 122, PO Box, CH-3001 Bern, Switzerland.

出版信息

Prev Vet Med. 2005 Nov 15;72(1-2):37-41; discussion 215-9. doi: 10.1016/j.prevetmed.2005.01.020. Epub 2005 Oct 6.

DOI:10.1016/j.prevetmed.2005.01.020
PMID:16213615
Abstract

We have genetically analyzed ruminant pestiviruses. All >150 bovine viral diarrhea (BVD) viruses isolated from cattle in Switzerland belonged to genotype 1, with subgenogroups e, h, k and b found in decreasing frequency. To date, representatives of subgenogroup k have been detected in Switzerland only. Despite serological evidence of Border disease in sheep, only few Border disease viruses have been isolated, all of which belong to the novel group 3. Serological evidence suggested that pestivirus infections may occur also in wild ruminants in Switzerland but no isolates are available for analysis. In addition, we describe two pestiviruses, one a cell culture contaminant and the other isolated from a buffalo, that cluster with a recently proposed novel pestivirus species.

摘要

我们对反刍动物瘟病毒进行了基因分析。从瑞士牛群中分离出的所有150多种牛病毒性腹泻(BVD)病毒均属于1型基因型,其中亚基因群e、h、k和b的检出频率依次降低。迄今为止,仅在瑞士检测到亚基因群k的代表毒株。尽管有血清学证据表明绵羊感染了边界病,但仅分离出少数边界病病毒,所有这些病毒均属于新的3组。血清学证据表明,瑞士的野生反刍动物也可能感染瘟病毒,但尚无分离株可供分析。此外,我们描述了两种瘟病毒,一种是细胞培养污染物,另一种是从水牛中分离出来的,它们与最近提出的一种新的瘟病毒物种聚集在一起。

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