Schulze-Röbbecke R, Buchholtz K
Institute of Hygiene, University of Bonn, Germany.
Appl Environ Microbiol. 1992 Jun;58(6):1869-73. doi: 10.1128/aem.58.6.1869-1873.1992.
An investigation was carried out to measure the heat susceptibility of opportunistic mycobacteria frequently isolated from domestic water supply systems. The study was conducted under standardized conditions designed to resemble those found in oligotrophic aquatic habitats. Strains of the following species were tested: Mycobacterium avium, M. chelonae, M. fortuitum, M. intracellulare, M. kansasii (two strains), M. marinum, M. phlei, M. scrofulaceum, and M. xenopi. Suspensions of the test strains were exposed to temperatures of 50, 55, 60, and 70 degrees C; samples were taken at defined intervals to determine the concentration of survivors. From these data, the decimal reduction times were calculated for each test strain and test temperature. The results indicate that M. kansasii is more susceptible to heat than Legionella pneumophila, whereas the heat susceptibilities of M. fortuitum, M. intracellulare, and M. marinum lie in the same order of magnitude as that of L. pneumophila. The strains of M. avium, M. chelonae, M. phlei, M. scrofulaceum, and M. xenopi were found to be more thermoresistant than L. pneumophila, with the highest resistance being found in M. xenopi. Thermal measures to control L. pneumophila may therefore not be sufficient to control the last five mycobacterial species in contaminated water systems.
开展了一项调查，以测定经常从家庭供水系统中分离出的机会性分枝杆菌的热敏感性。该研究在标准化条件下进行，这些条件旨在模拟贫营养水生栖息地中的条件。对以下菌种的菌株进行了测试：鸟分枝杆菌、龟分枝杆菌、偶然分枝杆菌、胞内分枝杆菌、堪萨斯分枝杆菌（两株）、海分枝杆菌、草分枝杆菌、瘰疬分枝杆菌和蟾分枝杆菌。将测试菌株的悬浮液暴露于50、55、60和70摄氏度的温度下；在规定的时间间隔取样以确定存活菌的浓度。根据这些数据，计算出每个测试菌株和测试温度下的十进制减少时间。结果表明，堪萨斯分枝杆菌比嗜肺军团菌对热更敏感，而偶然分枝杆菌、胞内分枝杆菌和海分枝杆菌的热敏感性与嗜肺军团菌处于同一数量级。发现鸟分枝杆菌、龟分枝杆菌、草分枝杆菌、瘰疬分枝杆菌和蟾分枝杆菌的菌株比嗜肺军团菌更耐热，其中蟾分枝杆菌的抗性最高。因此，控制嗜肺军团菌的热措施可能不足以控制受污染水系统中的后五种分枝杆菌。
