Barbour Krista A, Blumenthal James A
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Box 3119, Durham, NC 27710, USA.
Neurobiol Aging. 2005 Dec;26 Suppl 1:119-23. doi: 10.1016/j.neurobiolaging.2005.09.007. Epub 2005 Oct 11.
This article provides a review of the evidence supporting exercise as an effective treatment of depression in older adults. Depression is prevalent among older adults and is associated with significant morbidity, increased risk of mortality, and economic burden. Although effective treatments for depression exist (e.g., antidepressant medication, cognitive-behavioral therapy), the disorder remains inadequately treated for many older individuals. Recently, the use of exercise as a treatment for depression has received increased attention. Results of these studies suggest that exercise leads to a reduction in depressive symptoms when compared to wait list, social contact controls, and antidepressant medication. However, many studies have significant methodological limitations. In the present article, we include discussion of these limitations and provide suggestions for future research.
本文综述了支持运动作为老年抑郁症有效治疗方法的证据。抑郁症在老年人中很普遍，与高发病率、死亡风险增加和经济负担相关。尽管存在有效的抑郁症治疗方法（如抗抑郁药物、认知行为疗法），但对许多老年人来说，这种疾病仍未得到充分治疗。最近，运动作为抑郁症的一种治疗方法受到了越来越多的关注。这些研究结果表明，与等待名单、社交接触对照和抗抑郁药物相比，运动可减轻抑郁症状。然而，许多研究存在重大的方法学局限性。在本文中，我们讨论了这些局限性，并为未来的研究提供了建议。
