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美沙酮维持治疗4年前后阿片类药物依赖者每日营养比例的评估。

Assessment of daily nutrition ratios of opiate-dependent persons before and after 4 years of methadone maintenance treatment.

作者信息

Kolarzyk Emilia, Chrostek Maj Jan, Pach Dorota, Janik Anna, Kwiatkowski Jacek, Szurkowska Magdalena

机构信息

Department of Hygiene and Ecology, Jagiellonian University Medical College, Kraków, Poland.

出版信息

Przegl Lek. 2005;62(6):368-72.

Abstract

The aim of the study was the evaluation of the changes in nutritional habits of opiates dependent persons during 4 years of attendance in methadone maintenance treatment conducted by the Department of Toxicology of CMUJ in Kraków. These criteria were fulfilled by 30 persons (23 males and 7 females). They were examined before the methadone treatment and after 4 years of treatment. During Initial and final examinations for each of examined person the 24-hour recall had been performed three times. The information about daily supply of main nutrients (proteins, fats, fatty acids, carbohydrates, dietary fibre, cholesterol), minerals (calcium, iron, phosphorus, zinc, sodium) and vitamins (vitamin A, B1, B2, niacin, C) were obtained. The results were compared with daily norms (N) recommended on the safe level of intake. The normal range was established on the level +/-10% of normal values (+/-10% N). The changes between the results of following examinations were tested by using the t-student test. After 4 years of methadone treatment an increase in energy, vitamins, minerals and main nutritional ingredients intake was noted in women group. In men group a decrease in energy, proteins and carbohydrates intake was noted and fats intake, mainly unsaturated fatty acids, was increased. Vitamins were consumed in lower amounts and among minerals lower consumption in case of iron and sodium was noticed. In comparison with the recommended values in the initial examination in women group too low intake concerned fibre and vit. A, B,, calcium, iron, zinc and magnesium was noticed. In group of men too low intake (below recommended values) of energy, carbohydrates, fiber, vit. B1, B2, C, niacin, calcium and magnesium was noticed. After 4 years of methadone maintenance treatment in group of women too low intake only of vit. B1 and iron was noticed. In group of men it concerned vit. B1, B2, C, niacin and minerals such as calcium, iron, magnesium and zinc.

摘要

本研究的目的是评估在克拉科夫雅盖隆大学医学院毒理学系进行的为期4年的美沙酮维持治疗期间,阿片类药物依赖者营养习惯的变化。30人(23名男性和7名女性)符合这些标准。他们在美沙酮治疗前和治疗4年后接受了检查。在每次检查的初始和最终阶段,对每位受检者进行了三次24小时饮食回顾。获取了有关主要营养素(蛋白质、脂肪、脂肪酸、碳水化合物、膳食纤维、胆固醇)、矿物质(钙、铁、磷、锌、钠)和维生素(维生素A、B1、B2、烟酸、C)每日摄入量的信息。将结果与安全摄入量推荐的每日标准(N)进行比较。正常范围设定为正常值的±10%(±10%N)。使用t检验对后续检查结果之间的变化进行测试。美沙酮治疗4年后,女性组的能量、维生素、矿物质和主要营养成分摄入量增加。男性组的能量、蛋白质和碳水化合物摄入量减少,脂肪摄入量增加,主要是不饱和脂肪酸。维生素摄入量较低,在矿物质方面,铁和钠的摄入量较低。与初始检查中的推荐值相比,女性组中纤维和维生素A、B1、钙、铁、锌和镁的摄入量过低。在男性组中,能量、碳水化合物、纤维、维生素B1、B2、C、烟酸、钙和镁的摄入量过低(低于推荐值)。美沙酮维持治疗4年后,女性组仅维生素B1和铁的摄入量过低。在男性组中,涉及维生素B1、B2、C、烟酸以及钙、铁、镁和锌等矿物质。

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