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美沙酮维持治疗4年期间味觉偏好的变化。

The changes in taste preferences during 4 years period of methadone maintenance treatment.

作者信息

Kolarzyk Emilia, Jenner Bartosz, Szpanowska-Wohn Agnieszka, Pach Dorota, Szurkowska Magdalena

机构信息

Department of Hygiene and Ecology, Jagiellonian University Medical College, Kraków, Poland.

出版信息

Przegl Lek. 2005;62(6):378-81.

Abstract

The aim of the study was the analysis of the changes in the kind and the frequency of particular nutritional products consumption by opiate addicted persons during 4-year lasting methadone programme. There were 30 opiate addicted patients under examination (23 men and 7 women). Food consumption quality was estimated with the use of the Intake Frequency of Food Products Questionnaire. The examinations were performed before methadone administration had started, after 9 months and after 4 years of methadone maintenance treatment. Three categories of consumption frequency were established: rarely, moderately and often. The classification of different products was done with the use of hierarchic cluster analysis. For general illustration of the data the consumed products were compared by the means of hierarchical cluster analysis (this was done with the help of Euclidean distances and the Ward's algorithm). Then the k-means (with k=3) method was used in order to identify groups of products that were similarly often consumed. Each k-means analysis was performed separately for each examination. This was done in order to find out the products that change the cluster from one examination to another. Twenty labile products were identified. The examined products were moving between the adherent categories. This means that the consumption pattern undergoes some changes over the course of methadone therapy. Additionally, the analysis of the diet of this group of people shows improper and unhealthy nutritional behaviours: too big intake of sweets and too low intake of complex carbohydrates, fish and vegetable fats. This was especially visible at the beginning of the therapy, later this unfavourable diet habits changed but not to the desired level.

摘要

该研究的目的是分析在为期4年的美沙酮治疗项目中,阿片类药物成瘾者特定营养产品消费种类和频率的变化。有30名阿片类药物成瘾患者接受检查(23名男性和7名女性)。使用食品产品摄入频率问卷评估食物消费质量。检查在美沙酮给药开始前、给药9个月后以及美沙酮维持治疗4年后进行。确定了三类消费频率:很少、中等和经常。不同产品的分类采用层次聚类分析。为了总体说明数据,通过层次聚类分析比较所消费的产品(借助欧几里得距离和沃德算法完成)。然后使用k均值法(k = 3)来识别消费频率相似的产品组。每次检查都分别进行一次k均值分析。这样做是为了找出在不同检查中聚类发生变化的产品。确定了20种不稳定产品。所检查的产品在相关类别之间变动。这意味着在美沙酮治疗过程中消费模式会发生一些变化。此外,对这群人的饮食分析显示出不当和不健康的营养行为:甜食摄入量过大,复合碳水化合物、鱼类和植物脂肪摄入量过低。这在治疗开始时尤为明显,后来这种不良饮食习惯有所改变,但未达到理想水平。

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