Larner A J, Lendrum R
Medical Unit No. 1, Freeman Hospital, High Heaton, Newcastle-upon-Tyne.
Gut. 1992 Jun;33(6):860-1. doi: 10.1136/gut.33.6.860.
Oesophageal candidiasis was diagnosed incidentally at endoscopy in two patients receiving omeprazole therapy. There were no other predisposing factors for the development of candidiasis. The infection was resolved rapidly by anti-candidal therapy and by stopping omeprazole. These findings suggest that gastric acid secretion and physiological reflux of acid into the oesophagus may play a protective role in preventing candida infection.
两名接受奥美拉唑治疗的患者在内镜检查时偶然诊断出食管念珠菌病。念珠菌病的发生没有其他诱发因素。通过抗念珠菌治疗和停用奥美拉唑，感染迅速得到解决。这些发现表明胃酸分泌以及酸向食管的生理性反流可能在预防念珠菌感染中起保护作用。
