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公猪精子质量和生育力的候选基因标记

Candidate gene markers for sperm quality and fertility of boar.

作者信息

Lin C L, Ponsuksili S, Tholen E, Jennen D G J, Schellander K, Wimmers K

机构信息

Institute of Animal Breeding and Genetics, University of Bonn, D-53115 Bonn, Germany.

出版信息

Anim Reprod Sci. 2006 May;92(3-4):349-63. doi: 10.1016/j.anireprosci.2005.05.023. Epub 2005 Oct 19.

DOI:10.1016/j.anireprosci.2005.05.023
PMID:16242873
Abstract

Candidate genes gonadotropin releasing hormone receptor (GNRHR), prolactin (PRL), prolactin receptor (PRLR), follicle-stimulating hormone beta (FSHB), luteinizing hormone beta (LHB), follistatin (FST), inhibin alpha (INHA), inhibin beta A (INHBA) and inhibin beta B (INHBB) were investigated for their association with sperm quality traits of sperm concentration (SCON), motility (MOT), semen volume per ejaculate (VOL), plasma droplets rate (PDR), abnormal sperm rate (ASR) and fertility traits of non return rate (NRR) and number of piglets born alive (NBA). The experimental material included 356 boars of Pietrain (PI) and Pietrain x Hampshire (PI x HA). Analysis of variance revealed significant association of GNRHR with MOT (P = 0.0161), PDR (P = 0.0048) and ASR (P = 0.0201), INHBA was found to have significant effects on PDR (P = 0.0318) and ASR (P = 0.0067), INHBB was significant (P = 0.0360) for SCON trait. FSHB, FST, INHA, PRL, PRLR and LHB had no significant effects on any trait in this experiment.

摘要

研究了候选基因促性腺激素释放激素受体(GNRHR)、催乳素(PRL)、催乳素受体(PRLR)、促卵泡激素β(FSHB)、促黄体生成素β(LHB)、卵泡抑素(FST)、抑制素α(INHA)、抑制素βA(INHBA)和抑制素βB(INHBB)与精子质量性状(精子浓度(SCON)、活力(MOT)、每次射精精液体积(VOL)、血浆滴率(PDR)、异常精子率(ASR))以及繁殖性状(返情率(NRR)和产活仔数(NBA))之间的关联。实验材料包括356头皮特兰(PI)和皮特兰×汉普夏(PI×HA)公猪。方差分析显示,GNRHR与MOT(P = 0.0161)、PDR(P = 0.0048)和ASR(P = 0.0201)存在显著关联,发现INHBA对PDR(P = 0.0318)和ASR(P = 0.0067)有显著影响,INHBB对SCON性状显著(P = 0.0360)。在本实验中,FSHB、FST、INHA、PRL、PRLR和LHB对任何性状均无显著影响。

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