Zec Ronald F, Markwell Stephen J, Burkett Nicole R, Larsen Deb L
Center for Alzheimer Disease and Related Disorders, Southern Illinois University School of Medicine, Springfield, Illinois 62794, USA.
J Int Neuropsychol Soc. 2005 Oct;11(6):716-26. doi: 10.1017/S1355617705050897.
The longitudinal effects of age on confrontation naming using the 60-item Boston Naming Test (BNT) were studied in 541 "normal" elderly (ages 50-99). For participants with at least 4 annual assessments (n = 238), 150 were followed for > or =6 years, 81 for > or =8 years, and 43 for > or =10 years. A small practice effect (0.21 words, p = 0.06) and moderately high test-retest reliability were found when comparing the first 2 assessments, which were 9-15 months apart (r = 0.76, n = 353). Reliable change index scores indicated that an annual decline of > or =4 points on the BNT is needed for a statistically reliable decline in an individual. A gradient in the mean annual rate of change on the BNT was found with improvement in the 50s age group, no change in the 60s age group, and decline in the 70s and 80s age groups. When projected over 10 years, the magnitudes of the mean changes were relatively small, that is, a 1-word improvement for participants in their 50s and a 1.3-word decline for participants in their 70s. These findings demonstrate that lexical retrieval as measured by a visual object confrontation naming task is generally well preserved in aging with only subtle decline in the 7th and 8th decades of age.
我们对541名年龄在50至99岁之间的“正常”老年人进行了研究,以探讨年龄对使用60项波士顿命名测试(BNT)进行的视觉物体命名的纵向影响。对于至少接受了4次年度评估的参与者(n = 238),其中150人随访时间≥6年,81人随访时间≥8年,43人随访时间≥10年。在比较间隔9至15个月的前两次评估时,发现了较小的练习效应(0.21个单词,p = 0.06)以及中等偏高的重测信度(r = 0.76,n = 353)。可靠变化指数得分表明,个体在BNT上每年下降≥4分才具有统计学上可靠的下降趋势。在BNT上发现了平均年变化率的梯度,50多岁年龄组有改善,60多岁年龄组无变化,70多岁和80多岁年龄组下降。如果按10年推算,平均变化幅度相对较小,即50多岁的参与者有1个单词的改善,70多岁的参与者有1.3个单词的下降。这些发现表明,通过视觉物体命名任务测量的词汇检索能力在衰老过程中通常保持良好,仅在70岁和80岁时略有下降。