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汉坦病毒L、M和S基因组片段推导基因产物的比较。

Comparison of the deduced gene products of the L, M and S genome segments of hantaviruses.

作者信息

Antic D, Kang C Y, Spik K, Schmaljohn C, Vapalahti O, Vaheri A

机构信息

Department of Microbiology and Immunology, University of Ottawa, Faculty of Medicine, Ont., Canada.

出版信息

Virus Res. 1992 Jun;24(1):35-46. doi: 10.1016/0168-1702(92)90029-9.

DOI:10.1016/0168-1702(92)90029-9
PMID:1626424
Abstract

The amino acid sequences deduced from all currently available nucleotide sequences of hantaviruses are compared. Comparisons of three large (L), eight medium (M) and five small (S) genome segments are included. A consensus sequence is provided, allowing easy identification of conserved and unique gene regions. The viruses included in this report represent four serologically distinct hantaviruses which are capable of causing severe, moderate, mild or no human disease.

摘要

对从汉坦病毒所有现有核苷酸序列推导出来的氨基酸序列进行了比较。包括对三个大(L)、八个中(M)和五个小(S)基因组片段的比较。提供了一个共有序列,便于识别保守和独特的基因区域。本报告中纳入的病毒代表了四种血清学上不同的汉坦病毒,它们能够引起严重、中度、轻度或无人类疾病。

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