巴豆叶水提取物的抗炎活性。
Anti-inflammatory activity of Croton cuneatus aqueous extract.
作者信息
Suárez Alírica I, Blanco Zuleyma, Compagnone Reinaldo S, Salazar-Bookaman María M, Zapata Varlin, Alvarado Claudia
机构信息
Facultad de Farmacia, Universidad Central de Venezuela, Apartado 40109, Caracas, Venezuela.
出版信息
J Ethnopharmacol. 2006 Apr 21;105(1-2):99-101. doi: 10.1016/j.jep.2005.10.006. Epub 2005 Nov 28.
The aqueous extract of Croton cuneatus Klotz. (Euphorbiaceae), was tested for its antinociceptive effects using chemical and thermal test models in mice. Anti-inflammatory activity was determined in Sprague-Dawley rats in a model of acute plantar inflammation induced by bovine serum albumin. Croton cuneatus aqueous extract at doses of 7 mg/kg showed a significant anti-inflammatory effect compared with commonly used non-stereoidal drugs as ketoprofen, sodium diclofenac and ASA (acetylsalicylic acid).
用巴豆（大戟科）的水提取物，采用化学和热测试模型在小鼠身上测试其抗伤害感受作用。在牛血清白蛋白诱导的急性足底炎症模型中，在斯普拉格-道利大鼠身上测定其抗炎活性。与常用的非甾体类药物如酮洛芬、双氯芬酸钠和阿司匹林（乙酰水杨酸）相比，7毫克/千克剂量的巴豆水提取物显示出显著的抗炎作用。
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