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老年人髋部骨折手术术后死亡的相关危险因素:基于人群的研究方法。

Risk factors correlated with post-operative mortality for hip fracture surgery in the elderly: a population-based approach.

作者信息

Franzo Antonella, Francescutti Carlo, Simon Giorgio

机构信息

Agenzia Regionale della Sanità del Friuli Venezia Giulia, piazzale S. Maria della Misericordia 15 Udine, 33100, Italy.

出版信息

Eur J Epidemiol. 2005;20(12):985-91. doi: 10.1007/s10654-005-4280-9.

Abstract

OBJECTIVES

To estimate the effect of waiting time for surgery and volume of surgical activity on mortality in patients with hip fracture and to compare risk-adjusted outcomes between hospitals providing surgery for such patients.

DESIGN

Retrospective cohort study.

SETTING

Friuli Venezia Giulia, Italy.

PARTICIPANTS

A total of 6,629 elderly people who underwent surgery for hip fracture between 1st January 1996 and 31th December 2000.

MAIN OUTCOME MEASURES

In-hospital, 6-month and 1-year mortality rate.

RESULTS

In-hospital mortality rate was 5.4%. At six months, the mortality rate was 20.0%, and at 1 year 25.3%. Age, male sex, and comorbidity were significant predictors of mortality. Logistic regression analysis indicated that, after controlling for main patients risk factors and taking into account the hospital level variability, there was no significant association between increase in mortality rate and more than 1 day of waiting time for surgery (OR 0.90; 95% CI 0.58-1.40 for in-hospital mortality). One hospital had a significantly higher mortality rate than the others; high hospital volume for hip fracture surgery was associated with worse outcomes (OR 1.57; 95% CI 1.38-1.78 for in-hospital mortality). Mortality after hip fracture decreased significantly from 1996 to 2000 (OR 0.85; 95% CI 0.80-0.90).

CONCLUSIONS

Longer waiting time for surgery was not associated with mortality after adjusting for patient risk factors, and taking into account hospital level variability. Hospital level variability was statistically significant, and was partially explained by the total volume of hospital surgical activity. The decrease in mortality between 1996 and 2000 was confirmed by multivariate models.

摘要

目的

评估手术等待时间和手术量对髋部骨折患者死亡率的影响,并比较为这类患者提供手术的医院之间经风险调整后的结局。

设计

回顾性队列研究。

地点

意大利弗留利-威尼斯朱利亚。

参与者

1996年1月1日至2000年12月31日期间共6629例接受髋部骨折手术的老年人。

主要结局指标

住院、6个月和1年死亡率。

结果

住院死亡率为5.4%。6个月时,死亡率为20.0%,1年时为25.3%。年龄、男性性别和合并症是死亡率的显著预测因素。逻辑回归分析表明,在控制主要患者风险因素并考虑医院水平差异后,死亡率增加与手术等待时间超过1天之间无显著关联(住院死亡率的比值比为0.90;95%置信区间为0.58 - 1.40)。有一家医院的死亡率显著高于其他医院;髋部骨折手术量高与更差的结局相关(住院死亡率的比值比为1.57;95%置信区间为1.38 - 1.78)。1996年至2000年期间髋部骨折后的死亡率显著下降(比值比为0.85;95%置信区间为0.80 - 0.90)。

结论

在调整患者风险因素并考虑医院水平差异后,手术等待时间延长与死亡率无关。医院水平差异具有统计学意义,部分可由医院手术活动总量解释。多变量模型证实了1996年至2000年期间死亡率的下降。

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